Agudelo, Marisela

Agudelo, Marisela

Positions

Assistant Professor, Immunology and Nano-Medicine , Herbert Wertheim College of Medicine

placeholder image

selected publications

Article
- 2020
  
  Development of Multifunctional Biopolymeric Auto-Fluorescent Micro- and Nanogels as a Platform for Biomedical Applications
  Full Text via DOI: 10.3389/fbioe.2020.00315 Web of Science: 000535564500001
- 2018
  
  Ethanol-induced modulation of GPR55 expression in human monocyte-derived dendritic cells is accompanied by H4K12 acetylation
  Full Text via DOI: 10.1016/j.alcohol.2018.05.008 Web of Science: 000445443800004
- 2018
  
  Cigarette smoke promotes HIV infection of primary bronchial epithelium and additively suppresses CFTR function
  Full Text via DOI: 10.1038/s41598-018-26095-z Web of Science: 000432655800009
- 2018
  
  Oxidative Stress in HIV Infection and Alcohol Use: Role of Redox Signals in Modulation of Lipid Rafts and ATP-Binding Cassette Transporters
  Full Text via DOI: 10.1089/ars.2016.6830 Web of Science: 000418679900004
- 2018
  
  Summary of the 2016 Alcohol and Immunology Research Interest Group (AIRIG) meeting
  Full Text via DOI: 10.1016/j.alcohol.2017.07.005 Web of Science: 000422614100006
- 2018
  
  Trichostatin A Shows Transient Protection from Chronic Alcohol-Induced Reactive Oxygen Species (ROS) Production in Human Monocyte-Derived Dendritic Cells.
  Full Text via DOI: 10.4172/2329-6488.1000316
- 2017
  
  Novel detection of post-translational modifications in human monocyte-derived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac
  Full Text via DOI: 10.1038/s41598-017-11172-6 Web of Science: 000410064000072
- 2017
  
  Epigenetic Interactions between Alcohol and Cannabinergic Effects: Focus on Histone Modification and DNA Methylation.
  Full Text via DOI: 10.4172/2329-6488.1000259
- 2017
  
  HIV Infects Bronchial Epithelium and Suppresses Components of the Mucociliary Clearance Apparatus
  Full Text via DOI: 10.1371/journal.pone.0169161 Web of Science: 000391641500059
- 2016
  
  Characterization of Human Monocyte-derived Dendritic Cells by Imaging Flow Cytometry: A Comparison between Two Monocyte Isolation Protocols
  Full Text via DOI: 10.3791/54296 Web of Science: 000397844900023
- 2016
  
  Profile of Class I Histone Deacetylases (HDAC) by Human Dendritic Cells after Alcohol Consumption and In Vitro Alcohol Treatment and Their Implication in Oxidative Stress: Role of HDAC Inhibitors Trichostatin A and Mocetinostat
  Full Text via DOI: 10.1371/journal.pone.0156421 Web of Science: 000377184700043
- 2016
  
  Microglia-derived HIV Nef plus exosome impairment of the blood-brain barrier is treatable by nanomedicine-based delivery of Nef peptides
  Full Text via DOI: 10.1007/s13365-015-0397-0 Web of Science: 000371929900001
- 2015
  
  Alcohol and Cannabinoids Differentially Affect HIV Infection and Function of Human Monocyte-Derived Dendritic Cells (MDDC)
  Full Text via DOI: 10.3389/fmicb.2015.01452 Web of Science: 000366996900001
- 2015
  
  Investigation of Neuropathogenesis in HIV-1 Clade B and C Infection Associated with IL-33 and ST2 Regulation
  Full Text via DOI: 10.1021/acschemneuro.5b00156 Web of Science: 000361505100011
- 2015
  
  DJ1 expression downregulates in neuroblastoma cells (SK-N-MC) chronically exposed to HIV-1 and cocaine
  Full Text via DOI: 10.3389/fmicb.2015.00749 Web of Science: 000358881500001
- 2015
  
  HIV Subtypes B and C gp120 and Methamphetamine Interaction: Dopaminergic System Implicates Differential Neuronal Toxicity
  Full Text via DOI: 10.1038/srep11130 Web of Science: 000356087900001
- 2015
  
  Effect of Mild-to-Moderate Smoking on Viral Load, Cytokines, Oxidative Stress, and Cytochrome P450 Enzymes in HIV-Infected Individuals
  Full Text via DOI: 10.1371/journal.pone.0122402 Web of Science: 000353016500020
- 2015
  
  Alcohol Versus Cannabinoids: A Review of Their Opposite Neuro-Immunomodulatory Effects and Future Therapeutic Potentials.
  Full Text via DOI: 10.4172/2329-6488.1000184
- 2015
  
  Platelets Contribute to BBB Disruption Induced by HIV and Alcohol.
  Full Text via DOI: 10.4172/2329-6488.1000182
- 2015
  
  Effect of synthetic cannabinoids on blood–brain barrier
  Full Text via DOI: 10.7707/hmj.491
- 2015
  
  Preparation and characterization of anti-HIV nanodrug targeted to microfold cell of gut-associated lymphoid tissue
  Full Text via DOI: 10.2147/IJN.S68348 Web of Science: 000361620300001
- 2015
  
  Sustained-release nanoART formulation for the treatment of neuroAIDS
  Full Text via DOI: 10.2147/IJN.S76517 Web of Science: 000348984700001
- 2014
  
  Immunopathogenesis of HIV Infection in Cocaine Users: Role of Arachidonic Acid
  Full Text via DOI: 10.1371/journal.pone.0106348 Web of Science: 000341127500154
- 2014
  
  Immunoneuropathogenesis of HIV-1 clades B and C: Role of redox expression and thiol modification
  Full Text via DOI: 10.1016/j.freeradbiomed.2013.12.025 Web of Science: 000333490500014
- 2014
  
  Commentary on the Interactions of HIV and Alcohol in the Central Nervous System
  Full Text via DOI: 10.1111/acer.12326 Web of Science: 000332758200005
- 2014
  
  Enhanced blood-brain barrier transmigration using a novel transferrin embedded fluorescent magneto-liposome nanoformulation
  Full Text via DOI: 10.1088/0957-4484/25/5/055101 Web of Science: 000330191400001
- 2014
  
  Alcohol Abuse and HIV Infection: Role of DRD2
  Full Text via DOI: 10.2174/1570162X12666140721115045 Web of Science: 000340901200002
- 2013
  
  Cocaine Enhances HIV-1 Infectivity in Monocyte Derived Dendritic Cells by Suppressing microRNA-155
  Full Text via DOI: 10.1371/journal.pone.0083682 Web of Science: 000329325200106
- 2013
  
  Differential expression and functional role of cannabinoid genes in alcohol users
  Full Text via DOI: 10.1016/j.drugalcdep.2013.08.023 Web of Science: 000328240900071
- 2012
  
  Alcohol-induced serotonergic modulation: The role of histone deacetylases
  Full Text via DOI: 10.1016/j.alcohol.2012.03.005 Web of Science: 000309796200003
- 2012
  
  HIV-1 gp120 induces antioxidant response element-mediated expression in primary astrocytes: Role in HIV associated neurocognitive disorder
  Full Text via DOI: 10.1016/j.neuint.2011.06.011 Web of Science: 000310946100022
- 2012
  
  Inhibition of Nuclear Factor Erythroid 2-Related Factor 2 Exacerbates HIV-1 gp120-Induced Oxidative and Inflammatory Response: Role in HIV Associated Neurocognitive Disorder
  Full Text via DOI: 10.1007/s11064-012-0779-0 Web of Science: 000305949100011
- 2011
  
  Effects of Alcohol on Histone Deacetylase 2 (HDAC2) and the Neuroprotective Role of Trichostatin A (TSA)
  Full Text via DOI: 10.1111/j.1530-0277.2011.01492.x Web of Science: 000293027600022
- 2011
  
  Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS
  Full Text via DOI: 10.1007/s13365-011-0026-5 Web of Science: 000294356000004
- 2011
  
  HIV-1 Tat upregulates expression of histone deacetylase-2 (HDAC2) in human neurons: Implication for HIV-associated neurocognitive disorder (HAND)
  Full Text via DOI: 10.1016/j.neuint.2011.02.004 Web of Science: 000290139900007
- 2010
  
  Interactive role of human immunodeficiency virus type 1 (HIV-1) clade-specific Tat protein and cocaine in blood-brain barrier dysfunction: Implications for HIV-1-associated neurocognitive disorder
  Full Text via DOI: 10.3109/13550284.2010.499891 Web of Science: 000281613400005
- 2009
  
  Identification of transcription start sites and preferential expression of select CB2 transcripts in mouse and human B lymphocytes
  Full Text via DOI: 10.1007/s11481-009-9169-z
- 2008
  
  Cannabinoid receptor 2 (CB2) mediates immunoglobulin class switching from IgM to IgE in cultures of murine-purified B lymphocytes
  Full Text via DOI: 10.1007/s11481-007-9088-9
Book Chapter
- 2010
  
  Role of Dendritic Cells in HIV Infection: DC-SIGN and Novel Therapeutic Approaches. 167-177.
  Web of Science: 000284081600010
- 2010
  
  Role of dendritic cells in HIV infection: DC-SIGN and novel therapeutic approaches. 168-178.
Conference
- 2018
  
  DIFFERENTIAL EPIGENETIC EFFECTS OF ALCOHOL EXPOSURE AND THE TRANSIENT ANTI-OXIDANT PROTECTIVE EFFECT OF TRICHOSTATIN A, IN HUMAN DENDRITIC CELLS. 336A-336A.
  Web of Science: 000443221503261
- 2018
  
  DIFFERENTIAL EPIGENETIC EFFECTS OF ALCOHOL EXPOSURE AND TRANSIENT ANTI-OXIDANT PROTECTIVE EFFECT OF TRICHOSTATIN A, IN HUMAN DENDRITIC CELLS. 105A-105A.
  Web of Science: 000443221501346
- 2018
  
  CHRONIC ALCOHOL TREATMENT MODULATES GPR55 EXPRESSION THROUGH EPIGENETIC PATHWAYS IN HUMAN MONOCYTE-DERIVED DENDRITIC CELLS (MDDC).. S65-S65.
  Web of Science: 000434755400223
- 2018
  
  Imaging flow cytometry as a novel epigenetic tool to detect post-translational modifications and extracellular histone release induced by alcohol abuse. S28-S28.
  Web of Science: 000434755400097
- 2018
  
  CHRONIC ALCOHOL TREATMENT MODULATES GPR55 EXPRESSION THROUGH EPIGENETIC PATHWAYS IN HUMAN MONOCYTE-DERIVED DENDRITIC CELLS (MDDC).. S65-S65.
  Web of Science: 000429149100223
- 2018
  
  Imaging flow cytometry as a novel epigenetic tool to detect post-translational modifications and extracellular histone release induced by alcohol abuse. S28-S28.
  Web of Science: 000429149100097
- 2018
  
  Histone H4 lysine 12 acetylation leads to epigenetic regulation of the novel cannabinoid G-protein coupled receptor 55 (GPR55) in alcohol treated human dendritic cells. 89-89.
  Full Text via DOI: 10.1016/j.alcohol.2017.11.009 Web of Science: 000422614100016
- 2018
  
  Methylation profile of monocyte-derived dendritic cells after acute exposure to alcohol and synthetic cannabinoids. 89-90.
  Full Text via DOI: 10.1016/j.alcohol.2017.11.012 Web of Science: 000422614100019
- 2017
  
  ROLE OF H4K12AC TOWARDS STRESS RESPONSE MECHANISMS OF HUMAN MONOCYTE DERIVED DENDRITIC CELLS UNDER CHRONIC ALCOHOL STRESS. 186A-186A.
  Web of Science: 000402419601168
- 2017
  
  Exploring benefits of Methanandamide: towards developing a nanoformulation to combat against cannabinoids induced effects in HIV patients. S76-S76.
  Web of Science: 000414227700184
- 2017
  
  Functional effects of chronic alcohol stress in human monocyte-derived dendritic cells and the immunoprotective role of trichostatin A as demonstrated by single cell imaging flow cytometry. S39-S39.
  Web of Science: 000414227700086
- 2017
  
  Mass Spectrometry and Single Cell Imaging Flow Cytometry as screening tools to detect H3 and H4 post-translational modifications after acute and chronic alcohol exposure of human monocyte-derived dendritic cells (MDDC). S55-S55.
  Web of Science: 000414227700129
- 2017
  
  Alcohol induces epigenetic immunomodulation of human monocyte-derived dendritic cells. 70-70.
  Web of Science: 000397359400010
- 2017
  
  Histone H4 modification landscape due to chronic alcohol treatment in human monocyte-derived dendritic cells (MDDCs). 74-74.
  Web of Science: 000397359400024
- 2016
  
  EFFECT OF TOBACCO SMOKE AND HIV INFECTION ON MUCOCILIARY CLEARANCE. S48-S48.
  Web of Science: 000377566000123
- 2016
  
  EPIGENETIC MODULATIONS DUE TO CHRONIC ALCOHOL TREATMENT AND ITS ASSOCIATION WITH THE CANNABINERGIC PATHWAY.. S35-S36.
  Web of Science: 000377566000090
- 2016
  
  PERIPHERAL EFFECTS OF THE INTERACTION BETWEEN ALCOHOL AND THE HDAC INHIBITOR MOCETINOSTAT.. S3-S3.
  Web of Science: 000377566000003
- 2015
  
  EPIGENETIC MECHANISMS OF ALCOHOL-INDUCED IMMUNOMODULATION OF HUMAN MONOCYTE-DERIVED DENDRITIC CELL FUNCTION. 230A-230A.
  Web of Science: 000361637101400
- 2015
  
  Ex-vivo and in-vitro evidence of epigenetic mechanisms of alcohol abuse. S58-S58.
  Web of Science: 000367554100004
- 2015
  
  HIV and Morphine: Oxidative Stress Impact Cell Cycle Regulation and Neurodegeneration. S104-S104.
  Web of Science: 000367554100125
- 2015
  
  Marijuana promotes HIV replication in glia cells but inhibits HIV-exNef associated neuropathology. S68-S68.
  Web of Science: 000367554100030
- 2015
  
  Marijuana up-regulates HIV replication in microglia-like cells and restricts exNef-modulation of glia immune function. S65-S65.
  Web of Science: 000367554100022
- 2015
  
  Polydrug nanocarriers to treat opiate addiction and reduce HIV exNef-associated neuropathogenesis. S95-S95.
  Web of Science: 000367554100102
- 2015
  
  Sustained Release NanoART Formulation for the Treatment of NeuroAIDS. S77-S77.
  Web of Science: 000367554100055
- 2014
  
  HISTONE DEACETYLASE INHIBITORS MODULATE ALCOHOL-INDUCED CANNABINOID RECEPTORS AND OXIDATIVE STRESS PRODUCTION BY DENDRITIC CELLS. 152A-152A.
  Web of Science: 000337523700608
- 2014
  
  Association of Mental Disorders with Cocaine Use in HIV-1 Infected Females in South Florida. 39-40.
  Web of Science: 000333121600098
- 2014
  
  Bath salts alter synaptic plasticity gene expression in neurons. 62-62.
  Web of Science: 000333121600158
- 2014
  
  Cannabinoid Agonists Regulate Alcohol-induced Inflammation in Human Dendritic Cells. 3-4.
  Web of Science: 000333121600004
- 2014
  
  Immunopathogenesis of HIV-1 Infection in Cocaine users: Role of Arachidonic Acid. 55-55.
  Web of Science: 000333121600139
- 2014
  
  Polydrug mediated effects on HIV Nef plus exosome release and neuropathogenesis is modulated by Nef peptide magnetic nanocarriers. 46-47.
  Web of Science: 000333121600116
- 2014
  
  Role of HDAC2 and miR-485 in regulation of synaptic plasticity genes in HIV infection: Implication in HAND. 6-6.
  Web of Science: 000333121600011
- 2013
  
  DUAL MECHANISM ENHANCED BBB CROSSING BY TRANSFERRIN CONJUGATED FLUORESCENT MAGNETIC LIPOSOME.. 414-414.
  Web of Science: 000320312000098
- 2013
  
  DYSREGULATION OF IL-33 AND ST2 IN HIV1 B AND C CLADES.. 435-436.
  Web of Science: 000320312000159
- 2013
  
  HIV NEUROPATHOGENESIS: ROLE OF NEF plus EXOSOMES (EXNEF), METHAMPHETAMINE AND OPIATES. 430-431.
  Web of Science: 000320312000144
- 2013
  
  THE INTERACTIVE ROLE OF ALCOHOL AND CANNABINOIDS ON DENDRITIC CELL FUNCTION. 402-402.
  Web of Science: 000320312000062
- 2012
  
  Differential Regulation of IL-33 By HIV-1 B and C Clade Infection in Human Astrocytes (HA): Role in Neuropathogenesis.. S81-S81.
  Web of Science: 000302288800200
- 2012
  
  The Interactive Role of Histone Deacetylases and Cannabinoid Genes in Alcohol Abusers. S27-S28.
  Web of Science: 000302288800047
- 2011
  
  EXPRESSION OF HISTONE DEACETYLASE 2 (HDAC2) IN HUMAN MONOCYTE-DERIVED DENDRITIC CELLS (MDDCS) TREATED WITH ALCOHOL. 239A-239A.
  Web of Science: 000290804301409
- 2011
  
  Activation of the Antioxidant Defensive Enzymes Against HIV-1 gp120 are Mediated by Oxidative Stress and Elevated Intracellular Calcium Levels. S55-S56.
  Web of Science: 000302402500134
- 2011
  
  Association of Dopamine Receptor D2 C957T Gene SNP in Learning and Memory Among HIV-Positive Alcohol Abusers. S51-S51.
  Web of Science: 000302402500122
- 2011
  
  Differential Expression of Cannabinoid Genes in Alcoholics. S23-S23.
  Web of Science: 000302402500039
- 2011
  
  Differential Regulation of Neuroplasticity Associated Genes by HIV-1B and C Clades. S57-S57.
  Web of Science: 000302402500139
- 2011
  
  Differential Regulation of Thiol Modification by HIV-1 Clade B and C Protein. S57-S58.
  Web of Science: 000302402500140
- 2011
  
  Molecular Mechanism of Immunosuppression by Cocaine in HIV-1 Infected Subjects: Role of TLR3. S31-S31.
  Web of Science: 000302402500062
- 2010
  
  HIV-1 Tat upregulates expression of histone deacetylase-2 in human neurons: Implication for HAND. 75-76.
  Web of Science: 000283409800163
- 2010
  
  Human Immunodeficiency Virus type-1 Glade B and C gp120 Inhibit NMDA-receptor mediated induction of Arachidonic Acid: Implications on Neuro-AIDS. 76-76.
  Web of Science: 000283409800164
- 2010
  
  Effects of Alcohol on Cannabinoid (CB2) and Serotonin (5-HT3) Receptors in the Human Neuroblastoma Cell Line, SK-N-MC, and the Role of Histone Deacetylase 2 (HDAC2).. S39-S39.
  Web of Science: 000276567600089
- 2010
  
  Histone Deacetylase Activity in Development of HIV-Associated Neurocognitive Disorder.. S46-S46.
  Web of Science: 000276567600109
- 2010
  
  Neuropathogenic Mechanisms of HIV-1 Clade B and C: Role of Methamphetamine (METH).. S53-S53.
  Web of Science: 000276567600130
Other Scholarly Work
- 2017
  
  Novel detection of post-translational modifications in human monocytederived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac (vol 7, 11236, 2017)
  Full Text via DOI: 10.1038/s41598-017-16204-9 Web of Science: 000415984000001

principal investigator on

Synthetic cannabinoids and their effects on extracellular histone release and inflammation: using single cell imaging flow cytometry as a novel epigenetic tool awarded by FIU Foundation 2018 - 2020
EtOH-induced Immunomodulation: Role of Histone Deacetylases and Cannabinoid Genes awarded by Alcohol Abuse and Alcoholism 2015 - 2020
EtOH-induced Immunomodulation: Role of Histone Deacetylases and Cannabinoid Genes awarded by Alcohol Abuse and Alcoholism 2013 - 2015

co-principal investigator on

Florida Science Training and Research (STAR) Fellowship awarded by U.S. Department of Health & Human Servic 2015 - 2021

investigator on

Nano-delivery of methanandamide across BBB to block cannabinoid induced effects in HIV-1 infection awarded by National Institute on Drug Abuse 2015 - 2022
Nanotechnology Based Gene Editing to Eradicate HIV Brain Reservoir in Drug Abusers awarded by National Institute on Drug Abuse 2016 - 2022
Role of exosome extracellular vesicles in opiate abuse and HIV neuropathogenesis awarded by National Institute on Drug Abuse 2017 - 2020

visualizations

Co-author Network

Co-investigator Network

publication subject areas

Citation index-derived subject areas the researcher has published in