Chand, Hitendra

Hitendra Chand
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Positions

Associate Professor, Immunology and Nano-Medicine , Herbert Wertheim College of Medicine

Contact Info

hchand@fiu.edu

selected publications

Article
- 2021
  
  HIV-1 Productively Infects and Integrates in Bronchial Epithelial Cells. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 10.
  Full Text via DOI: 10.3389/fcimb.2020.612360 Web of Science: 000619020700001
- 2021
  
  SARS-CoV-2 Infection in the Central and Peripheral Nervous System-Associated Morbidities and Their Potential Mechanism. MOLECULAR NEUROBIOLOGY.
  Full Text via DOI: 10.1007/s12035-020-02245-1 Web of Science: 000607527000002
- 2020
  
  Differential plasma exosomal long non-coding RNAs expression profiles and their emerging role in E-cigarette users, cigarette, waterpipe, and dual smokers. PLOS ONE. 15.
  Full Text via DOI: 10.1371/journal.pone.0243065 Web of Science: 000598620100008
- 2020
  
  A long noncoding RNA antisense to ICAM-1 is involved in allergic asthma associated hyperreactive response of airway epithelial cells. MUCOSAL IMMUNOLOGY.
  Full Text via DOI: 10.1038/s41385-020-00352-9 Web of Science: 000584995500001
- 2020
  
  Gestational Exposure to Cigarette Smoke Suppresses the Gasotransmitter H2S Biogenesis and the Effects Are Transmitted Transgenerationally. FRONTIERS IN IMMUNOLOGY. 11.
  Full Text via DOI: 10.3389/fimmu.2020.01628 Web of Science: 000561369200001
- 2020
  
  Development of Multifunctional Biopolymeric Auto-Fluorescent Micro- and Nanogels as a Platform for Biomedical Applications. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 8.
  Full Text via DOI: 10.3389/fbioe.2020.00315 Web of Science: 000535564500001
- 2020
  
  Pulmonary Toxicity and the Pathophysiology of Electronic Cigarette, or Vaping Product, Use Associated Lung Injury. FRONTIERS IN PHARMACOLOGY. 10.
  Full Text via DOI: 10.3389/fphar.2019.01619 Web of Science: 000510030100001
- 2020
  
  Acetylcholinesterase Inhibitor Pyridostigmine Bromide Attenuates Gut Pathology and Bacterial Dysbiosis in a Murine Model of Ulcerative Colitis. DIGESTIVE DISEASES AND SCIENCES. 65:141-149.
  Full Text via DOI: 10.1007/s10620-019-05838-6 Web of Science: 000511968600022
- 2019
  
  Nontoxic amphiphilic carbon dots as promising drug nanocarriers across the blood-brain barrier and inhibitors of beta-amyloid. NANOSCALE. 11:22387-22397.
  Full Text via DOI: 10.1039/c9nr08194a Web of Science: 000507989900026
- 2019
  
  TGF-beta 1 increases viral burden and promotes HIV-1 latency in primary differentiated human bronchial epithelial cells. SCIENTIFIC REPORTS. 9.
  Full Text via DOI: 10.1038/s41598-019-49056-6 Web of Science: 000483017100031
- 2018
  
  Cigarette smoke and HIV synergistically affect lung pathology in cynomolgus macaques. JOURNAL OF CLINICAL INVESTIGATION. 128.
  Full Text via DOI: 10.1172/JCI121935 Web of Science: 000452071300027
- 2018
  
  A Small Molecule BH3-mimetic Suppresses Cigarette Smoke-Induced Mucous Expression in Airway Epithelial Cells. SCIENTIFIC REPORTS. 8.
  Full Text via DOI: 10.1038/s41598-018-32114-w Web of Science: 000444571200004
- 2018
  
  Noxa/HSP27 complex delays degradation of ubiquitylated IkB alpha in airway epithelial cells to reduce pulmonary inflammation. MUCOSAL IMMUNOLOGY. 11.
  Full Text via DOI: 10.1038/mi.2017.117 Web of Science: 000433899600014
- 2018
  
  IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells. SCIENTIFIC REPORTS. 8.
  Full Text via DOI: 10.1038/s41598-017-18884-9 PMID: 29323189 Web of Science: 000419940000029
- 2017
  
  Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity. COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 14:228-237.
  Full Text via DOI: 10.1080/15412555.2016.1262340 PMID: 28026993 Web of Science: 000398033800013
- 2017
  
  Gestational Exposure to Sidestream (Secondhand) Cigarette Smoke Promotes Transgenerational Epigenetic Transmission of Exacerbated Allergic Asthma and Bronchopulmonary Dysplasia. JOURNAL OF IMMUNOLOGY. 198:3815-3822.
  Full Text via DOI: 10.4049/jimmunol.1700014 PMID: 28381639 Web of Science: 000401137200006
- 2016
  
  T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways. RESPIRATORY RESEARCH. 17.
  Full Text via DOI: 10.1186/s12931-016-0446-0 PMID: 27765038 Web of Science: 000385976200001
Book Chapter
- 2019
  
  Cell-Line-Based Studies of Nanotechnology Drug-Delivery Systems: A Brief Review. NANOCARRIERS FOR DRUG DELIVERY: NANOSCIENCE AND NANOTECHNOLOGY IN DRUG DELIVERY. 375-393.
  Full Text via DOI: 10.1016/B978-0-12-814033-8.00012-6 Web of Science: 000472668000013
Letter
- 2020
  
  Metabolomics to Predict Antiviral Drug Efficacy in COVID-19. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 396-398.
  Full Text via DOI: 10.1165/rcmb.2020-0206LE Web of Science: 000567767500015
- 2017
  
  Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1456-+.
  Full Text via DOI: 10.1016/j.jaci.2017.05.038 PMID: 28784260 Web of Science: 000414304300032
Meeting Abstract
- 2018
  
  Bio-distribution and bio-safety assessment of magneto-electric nanoparticles in non-human primate. JOURNAL OF NEUROVIROLOGY.
  Web of Science: 000434755400139
- 2018
  
  Intranasal Nanodelivery of Oxytocin to Treat Drug Addiction in HIV Patients using CRISPR Gene Editing. JOURNAL OF NEUROVIROLOGY.
  Web of Science: 000434755400134
- 2018
  
  Cigarette Smoke Exposure Alters the Airway Epithelial Cell Fate by Modulating Mitochondrial Morphology and Bcl-2 Levels. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000449980305355
- 2018
  
  Intranasal Nanodelivery of Oxytocin to Treat Drug Addiction in HIV Patients using CRISPR Gene Editing. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S39-S39.
  Web of Science: 000429149100134
- 2018
  
  Mucoobstructive Lung Disease in the Era of Antiretroviral Therapy - A One-Two Blow of Tobacco Smoke Exposure and HIV Infection. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000449980304571
- 2018
  
  The Bcl-2 Family Protein, Noxa, Inhibits NF-kappa B-Mediated Inflammation in Airway Epithelia by Delaying I kappa B alpha Degradation. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000449978904487
- 2018
  
  Transcriptomic Analysis of Early Airway Epithelial Inflammatory Responses. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000449978900335
- 2017
  
  Development and Delivery of Intranasal Cas9/gRNA Aerosol Nanoformulation to Eradicate Latent HIV-1 in CNS. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S58-S59.
  Web of Science: 000414227700139
Review
- 2020
  
  Cellular stress responses and dysfunctional Mitochondrial-cellular senescence, and therapeutics in chronic respiratory diseases. REDOX BIOLOGY.
  Full Text via DOI: 10.1016/j.redox.2020.101443 Web of Science: 000537265700004
- 2020
  
  Role of Non-Coding RNAs in Lung Circadian Clock Related Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
  Full Text via DOI: 10.3390/ijms21083013 Web of Science: 000535565300355
- 2019
  
  Long Noncoding Transcriptome in Chronic Obstructive Pulmonary Disease. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 678-688.
  Full Text via DOI: 10.1165/rcmb.2019-0184TR Web of Science: 000499728500007
- 2019
  
  Nanoparticle-mediated approaches for Alzheimer's disease pathogenesis, diagnosis, and therapeutics. JOURNAL OF CONTROLLED RELEASE. 125-140.
  Full Text via DOI: 10.1016/j.jconrel.2019.10.034 Web of Science: 000499615300012

principal investigator on

Targeting Hyperplastic Airway Cells Using a Small Molecule Inhibitor awarded by National Institute of Allergy and Infectious Diseases 2017 - 2018
Targeting Chronic Mucous Hypersecretion Using a Small Molecule Inhibitor awarded by American Lung Association 2016 - 2018

investigator on

Intranasal Nanodelivery of Oxytocin to Treat Morphine Addiction in HIV Patients by Gene Editing awarded by National Institute on Drug Abuse 2017 - 2019

teaching activities

GMS6904-01: Introduction to Scientific Writing Spring Term 2019
GMS6904-01: Introduction to Scientific Writing Spring Term 2019
GMS6940-02: Supervised Teaching in Biomedical Science Fall Term 2019
GMS6940-02: Supervised Teaching in Biomedical Science Fall Term 2019
GMS6940-02: Supervised Teaching in Biomedical Science Fall Term 2019
GMS6940-02: Supervised Teaching in Biomedical Science Fall Term 2019
GMS6940-02: Supervised Teaching in Biomedical Science Fall Term 2019
GMS6979-02: Research Credits Fall Term 2019
GMS6979-02: Research Credits Fall Term 2019
GMS6979-02: Research Credits Fall Term 2019
GMS6979-02: Research Credits Fall Term 2019
GMS6979-02: Research Credits Fall Term 2019

full name

Hitendra Chand

ORCID iD

https://orcid.org/0000-0002-0574-9307 (confirmed)

visualizations

Recent publications and grants in Scholars@FIU

Co-author Network

Co-investigator Network

publication subject areas

Allergy
Biochemistry & Molecular Biology
Cell Biology
Chemistry
Gastroenterology & Hepatology
Immunology
Materials Science
Neurosciences & Neurology
Pharmacology & Pharmacy
Physics
Research & Experimental Medicine
Respiratory System
Science & Technology - Other Topics
Virology

Citation index-derived subject areas the researcher has published in