De Hendonca Chaves, Paulo H

De Hendonca Chaves, Paulo H
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Positions

Associate Professor, Translational Medicine , Herbert Wertheim College of Medicine

Contact Info

pdehendo@fiu.edu

overview

Paulo H. M. Chaves, MD, PhD is a geriatrician and clinical epidemiologist. He holds the endowed Leon Medical Centers Eminent Scholar Chair in Geriatrics in the Hebert Wertheim College of Medicine, and serves as Director of the Benjamin Leon Center for Geriatric Research and Education at FIU. Dr. Chaves led, in strategic partnership with Leon Medical Centers, the launch of the Leon Medical Centers Annual Geriatrics Conference, a major continuing medical education (CME) program that provides state-of-art updates on current topics relevant for physicians involved with the healthcare of older adults.

Before coming to FIU, Dr. Chaves served as the director of the Epidemiology of Aging program at Johns Hopkins Bloomberg School of Public Health, and co-investigator and/or principal investigator of the Hopkins site of multicenter, National Institutes of Health-funded population-based studies of older adults.

selected publications

Article
- 2020
  
  Intact and C-Terminal FGF23 Assays-Do Kidney Function, Inflammation, and Low Iron Influence Relationships With Outcomes?. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 105.
  Full Text via DOI: 10.1210/clinem/dgaa665 Web of Science: 000584547800085
- 2020
  
  Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index. JAMA NETWORK OPEN. 3.
  Full Text via DOI: 10.1001/jamanetworkopen.2020.23242 Web of Science: 000588111700007
- 2020
  
  Association of serum uromodulin with mortality and cardiovascular disease in the elderly-the Cardiovascular Health Study. NEPHROLOGY DIALYSIS TRANSPLANTATION. 35:1399-1405.
  Full Text via DOI: 10.1093/ndt/gfz008 Web of Science: 000593119400019
- 2020
  
  Examining the causal mediating role of brain pathology on the relationship between diabetes and cognitive impairment: the Cardiovascular Health Study. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY.
  Full Text via DOI: 10.1111/rssa.12570 Web of Science: 000531398500001
- 2020
  
  Association of Nonobstructive Chronic Bronchitis With Respiratory Health Outcomes in Adults. JAMA INTERNAL MEDICINE. 180:676-686.
  Full Text via DOI: 10.1001/jamainternmed.2020.0104 Web of Science: 000534043600013
- 2020
  
  Discrepancy in Frailty Identification: Move Beyond Predictive Validity. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 75:387-393.
  Full Text via DOI: 10.1093/gerona/glz052 Web of Science: 000537440500025
- 2019
  
  Association of serum and urinary uromodulin and their correlates in older adults-The Cardiovascular Health Study. NEPHROLOGY.
  Full Text via DOI: 10.1111/nep.13688 Web of Science: 000504575300001
- 2019
  
  Association of Serum Uromodulin With ESKD and Kinney Function Decline in the Elderly: The Cardiovascular Health Study. AMERICAN JOURNAL OF KIDNEY DISEASES. 74:501-509.
  Full Text via DOI: 10.1053/j.ajkd.2019.02.024 Web of Science: 000486606900012
- 2019
  
  Discriminative Accuracy of FEV1: FVC Thresholds for COPD-Related Hospitalization and Mortality. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 321:2438-2447.
  Full Text via DOI: 10.1001/jama.2019.7233 Web of Science: 000473009700022
- 2019
  
  Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies. CIRCULATION. 139:2422-2436.
  Full Text via DOI: 10.1161/CIRCULATIONAHA.118.038908 Web of Science: 000469018300011
- 2019
  
  Role of Late-Life Depression in the Association of Subclinical Cardiovascular Disease With All-Cause Mortality: Cardiovascular Health Study. JOURNAL OF AGING AND HEALTH. 31:652-666.
  Full Text via DOI: 10.1177/0898264317744921 Web of Science: 000461623000006
- 2018
  
  Serial circulating omega 3 polyunsaturated fatty acids and healthy ageing among older adults in the Cardiovascular Health Study: prospective cohort study. BMJ-BRITISH MEDICAL JOURNAL. 363.
  Full Text via DOI: 10.1136/bmj.k4067 Web of Science: 000448263800002
- 2018
  
  Balance and Gait of Frail, Pre-Frail, and Robust Older Hispanics. GERIATRICS. 3.
  Full Text via DOI: 10.3390/geriatrics3030042 Web of Science: 000461145500011
- 2018
  
  Late-Life Depressive Symptoms as Partial Mediators in the Associations between Subclinical Cardiovascular Disease with Onset of Mild Cognitive Impairment and Dementia. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY. 26.
  Full Text via DOI: 10.1016/j.jagp.2017.11.004 Web of Science: 000432439200009
- 2017
  
  Bone Mineral Density and Risk of Heart Failure in Older Adults: The Cardiovascular Health Study. JOURNAL OF THE AMERICAN HEART ASSOCIATION. 6.
  Full Text via DOI: 10.1161/JAHA.116.004344 Web of Science: 000399322900011
- 2017
  
  The Association of Vitamin D Deficiency and Incident Frailty in Older Women: The Role of Cardiometabolic Diseases. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 65.
  Full Text via DOI: 10.1111/jgs.14677 Web of Science: 000397794300030
- 2016
  
  Can a Healthy Lifestyle Compress the Disabled Period in Older Adults?. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 64.
  Full Text via DOI: 10.1111/jgs.14314 Web of Science: 000387018500033
- 2016
  
  omega-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease Pooling Project of 19 Cohort Studies. JAMA INTERNAL MEDICINE. 176.
  Full Text via DOI: 10.1001/jamainternmed.2016.2925 Web of Science: 000381145000027
- 2016
  
  Vitamin D and Risk of Neuroimaging Abnormalities. PLOS ONE. 11.
  Full Text via DOI: 10.1371/journal.pone.0154896 Web of Science: 000376587300105
- 2016
  
  Vitamin D and Memory Decline: Two Population-Based Prospective Studies. JOURNAL OF ALZHEIMERS DISEASE. 50.
  Full Text via DOI: 10.3233/JAD-150811 Web of Science: 000371053400015
- 2015
  
  Cardiovascular and Mortality Outcomes in the Elderly With Impaired Cardiac and Pulmonary Function: The Cardiovascular Health Study (CHS). JOURNAL OF THE AMERICAN HEART ASSOCIATION. 4.
  Full Text via DOI: 10.1161/JAHA.115.002308 Web of Science: 000369947700042
- 2015
  
  Urinary uromodulin, kidney function, and cardiovascular disease in elderly adults. KIDNEY INTERNATIONAL. 88.
  Full Text via DOI: 10.1038/ki.2015.192 Web of Science: 000364799200025
- 2015
  
  Urine Collagen Fragments and CKD Progression-The Cardiovascular Health Study. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 26.
  Full Text via DOI: 10.1681/ASN.2014070696 Web of Science: 000362156700021
- 2015
  
  Microvascular and Macrovascular Abnormalities and Cognitive and Physical Function in Older Adults: Cardiovascular Health Study. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 63.
  Full Text via DOI: 10.1111/jgs.13594 Web of Science: 000363804800021
- 2015
  
  One-Year Change in the Japanese Version of the Montreal Cognitive Assessment Performance and Related Predictors in Community-Dwelling Older Adults. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 63.
  Full Text via DOI: 10.1111/jgs.13595 Web of Science: 000363804800019
- 2015
  
  Monitoring 6-Month Trajectory of Grip Strength Improves the Prediction of Long-Term Change in Grip Strength in Disabled Older Women. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 70.
  Full Text via DOI: 10.1093/gerona/glu149 Web of Science: 000350122200013
- 2015
  
  Association of mitochondrial DNA levels with frailty and all-cause mortality. JOURNAL OF MOLECULAR MEDICINE-JMM. 93.
  Full Text via DOI: 10.1007/s00109-014-1233-3 Web of Science: 000349288800007
- 2014
  
  Prognostic Implications of Microvascular and Macrovascular Abnormalities in Older Adults: Cardiovascular Health Study. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 69.
  Full Text via DOI: 10.1093/gerona/glu074 Web of Science: 000348339800006
- 2014
  
  Vitamin D and the risk of dementia and Alzheimer disease. NEUROLOGY. 83.
  Full Text via DOI: 10.1212/WNL.0000000000000755 Web of Science: 000341692500011
- 2014
  
  Physical Activity and Heart Rate Variability in Older Adults The Cardiovascular Health Study. CIRCULATION. 129.
  Full Text via DOI: 10.1161/CIRCULATIONAHA.113.005361 Web of Science: 000337277000010
- 2013
  
  Soluble CD14 Genomewide Association Analysis and Relationship to Cardiovascular Risk and Mortality in Older Adults. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 33.
  Full Text via DOI: 10.1161/ATVBAHA.112.300421 Web of Science: 000312392500024
- 2012
  
  Patterns of 12-Year Change in Physical Activity Levels in Community-Dwelling Older Women: Can Modest Levels of Physical Activity Help Older Women Live Longer?. AMERICAN JOURNAL OF EPIDEMIOLOGY. 176.
  Full Text via DOI: 10.1093/aje/kws125 Web of Science: 000309073300012
- 2012
  
  Persistence and Remission of Musculoskeletal Pain in Community-Dwelling Older Adults: Results from the Cardiovascular Health Study. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 60.
  Full Text via DOI: 10.1111/j.1532-5415.2012.04082.x Web of Science: 000307542300001
Letter
- 2015
  
  Response to Letter Regarding Article, "Physical Activity and Heart Rate Variability in Older Adults: The Cardiovascular Health Study". CIRCULATION.
  Full Text via DOI: 10.1161/CIRCULATIONAHA.114.012825 Web of Science: 000349539200004
Meeting Abstract
- 2020
  
  Association of low-intensity smoking with respiratory and lung cancer mortality. EUROPEAN RESPIRATORY JOURNAL.
  Full Text via DOI: 10.1183/13993003.congress-2020.4389 Web of Science: 000606501407372
- 2020
  
  Risk Score for Subclinical COPD: The NHLBI Pooled Cohorts Study. EUROPEAN RESPIRATORY JOURNAL.
  Full Text via DOI: 10.1183/13993003.congress-2020.3760 Web of Science: 000606501407162
- 2020
  
  Associations Between Lung Function Impairment and Incident Heart Failure with Preserved Ejection Fraction (HFpEF): The NHLBI Pooled Cohorts Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000556622803051
- 2020
  
  Associations Between Metabolic Syndrome and Longitudinal Respiratory Outcomes: The NHLBI Pooled Cohorts Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000556622803043
- 2020
  
  Smoking Reduction Among Current Smokers and Cause-Specific Mortality: The NHLBI Pooled Cohorts Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000556622805386
- 2019
  
  Late Breaking Abstract - Ten-year risk score for COPD: the NHLBI pooled cohorts study. EUROPEAN RESPIRATORY JOURNAL.
  Full Text via DOI: 10.1183/13993003.congress-2019.PA3318 Web of Science: 000507372404141
- 2019
  
  OSTEOSARCOPENIA PHENOTYPE AND FRAILTY STATUS BY CHS AND SOF CRITERIA. OSTEOPOROSIS INTERNATIONAL. S350-S350.
  Web of Science: 000475685501205
- 2019
  
  Social Isolation and Incident Disability with Activities of Daily Living (ADL): Clinical Implications. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. S222-S222.
  Web of Science: 000463149000641
- 2019
  
  Asthma COPD Overlap Is Associated with Increased Mortality and Respiratory Events, the NHLBI Pooled Cohorts Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000466776705377
- 2019
  
  Comparing Risk Factors for Lung Cancer Mortality Among Men and Women: The NHLBI Pooled Cohorts Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000466771100174
- 2018
  
  Prognostic Significance of Non-Obstructive Chronic Bronchitis (NCB) in the General Population: the NHLBI Pooled Cohorts Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.
  Web of Science: 000449980305477
- 2017
  
  CIRCULATING N-3 POLYUNSATURATED-FATTY ACIDS AND THE MAINTENANCE OF HEALTHY AGEING IN OLDER ADULTS, THE CARDIOVASCULAR HEALTH STUDY. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH.
  Full Text via DOI: 10.1136/jech-2017-SSMAbstracts.68 Web of Science: 000419440300069
- 2017
  
  OSTEOSARCOPENIA IS MORE ASSOCIATED WITH DISABILITY COMPARED TO SARCOPENIA OR OSTEOPOROSIS ALONE, IN OLDER ADULTS WITH CARDIOVASCULAR DISEASE: DATA FROM SARCOS STUDY. OSTEOPOROSIS INTERNATIONAL.
  Web of Science: 000406278600398
- 2017
  
  THE ASSOCIATION OF OSTEOSARCOPENIA, SARCO-PENIA AND OSTEOPOROSIS WITH WEAKNESS AND MOBILITY IN OLDER ADULTS WITH CARDIOVASCULAR DISEASE: DATA FROM SARCOS STUDY. OSTEOPOROSIS INTERNATIONAL.
  Web of Science: 000406278600386
- 2017
  
  Association of Osteosarcopenia, Sarcopenia EWGSOP alone and Osteoporosis alone with Mobility in older adults: Data from SARCOS study. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY.
  Web of Science: 000402876300139
- 2016
  
  Systolic blood pressure changes in hypertensive patients participating in a novel primary-care-based wellness program designed for Hispanics 65 years and older in South Florida. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY.
  Web of Science: 000374763800531
- 2015
  
  BURDEN OF FALLS-RELATED EMERGENCY DEPARTMENT UTILIZATION AND COST BY OLDER ADULTS IN FLORIDA IN 2013. GERONTOLOGIST.
  Web of Science: 000374222703127
- 2013
  
  HEART RATE VARIABILITY AND 9-YEAR COGNITIVE DECLINE IN THE CARDIOVASCULAR HEALTH STUDY. GERONTOLOGIST.
  Web of Science: 000327442103028
- 2013
  
  Heart Failure and Mortality in the Elderly With Impaired Cardiac and Pulmonary Function. CIRCULATION.
  Web of Science: 000332162901303
- 2013
  
  LIFESTYLE FACTORS AND ACTIVE LIFE EXPECTANCY IN THE CARDIOVASCULAR HEALTH STUDY. GERONTOLOGIST.
  Web of Science: 000327442102306
- 2013
  
  THRESHOLD EFFECT OF MULTISYSTEM PHYSIOLOGICAL DYSREGULATION ON THE DEVELOPMENT OF FRAILTY IN OLDER WOMEN. GERONTOLOGIST.
  Web of Science: 000327442106218
Review
- 2016
  
  Prevention of falls in older people living in the community. BMJ-BRITISH MEDICAL JOURNAL.
  Full Text via DOI: 10.1136/bmj.i1419 PMID: 27125497 Web of Science: 000375483900001

principal investigator on

Advancing Primary Care Delivery to Medicare and Dual Eligible Beneficiaries in South Florida awarded by Leon Medical Centers 2019 - 2023
Hispanic community Health Study / Study of Latinos awarded by Albert Einstein College of Medicine YU 2018
Institute on Aging and Health Appropriation awarded by Florida Department of Health 2014 - 2015
Clinical Significance of Short-term Change and Variability of Grip Strength awarded by National Institute on Aging 2012 - 2015

investigator on

Bristol Myers Squibb Foundation Diversity in Clinical Trials Career Development Program - Multicenter Phase II Study of Pomalidomide Monotherapy in Kaposi Sarcoma: A Trial of the AIDS Malignancy Consortium (AMC) awarded by Bristol-Myers Squibb 2021 - 2023

full name

Paulo H De Hendonca Chaves

ORCID iD

https://orcid.org/0000-0001-8013-7928 (confirmed)

visualizations

Recent publications and grants in Scholars@FIU

Co-author Network

Co-investigator Network