Godavarty, Anuradha
- Associate Professor, Biomedical Engineering , College of Engineering and Computing
Overview
overview
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Dr. Anuradha Godavarty graduated with a PhD in Chemical Engineering from Texas A&M University in 2003. She worked as a Post-Doc at University of Vermont’s Department of Computer Science in 2003-2004. In Aug 2004, Dr. Godavarty joined FIU as an Assistant Professor in Biomedical Engineering. In Aug 2010, she was tenured and promoted to Associate Professor in Biomedical Engineering at FIU. Her research interests are in optical imaging technologies towards breast cancer imaging, functional brain mapping, and wound imaging applications (both instrument development as well as computational analysis).
Dr. Godavarty’s research work focuses in the area of optical-based molecular imaging (diffuse optical and fluorescence-enhanced optical imaging) and tomography. Optical imaging is based on the principles of near-infrared light propagation in scattering media (such as biological tissues) and the use of external fluorescent contrast agents to better differentiate normal and diseased tissues based on the differences in their optical properties. The research work requires an understanding of transport phenomena in biological systems, application of experimental skills towards instrument development, incorporation of optimization and mathematical tools towards image reconstructions, and development of biomedical aspects of engineering towards practical applications, such as cancer diagnostics, wound imaging, functional brain mapping.
research interests
- Diagnostic Bioimaging Sensor Systems; Near-infrared optical imaging; device development; wound imaging; smartphone imaging technologies; diabetic ulcers; radiation dermatitis; radiation mucositis
Scholarly & Creative Works
selected publications
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Article
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2022Assessment of Tissue Oxygenation and Radiation Dermatitis Pre-, During, and Post-Radiation Therapy in Breast Cancer PatientsFull Text via DOI: 10.3389/fonc.2022.879032 Web of Science: 000830392300001
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2021Development of a Smartphone-Based Optical Device to Measure Hemoglobin Concentration Changes for Remote Monitoring of WoundsFull Text via DOI: 10.3390/bios11060165 Web of Science: 000665291300001
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2020Physiological wound assessment from coregistered and segmented tissue hemoglobin mapsFull Text via DOI: 10.1364/JOSAA.394985 Web of Science: 000555713900002
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2019Tissue Oxygenation Changes to Assess Healing in Venous Leg Ulcers Using Near-Infrared Optical ImagingFull Text via DOI: 10.1089/wound.2018.0880 Web of Science: 000469484100001
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2019Breath-Hold Paradigm to Assess Variations in Oxygen Flow in Diabetic Foot Ulcers Using a Noncontact Near-Infrared Optical ScannerFull Text via DOI: 10.1089/wound.2018.0922 Web of Science: 000464272300001
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2019Development and Validation of a Smartphone-Based Near-Infrared Optical Imaging Device to Measure Physiological Changes In-VivoFull Text via DOI: 10.3390/mi10030180 Web of Science: 000464418400002
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2017Assessing the Healing of Venous Leg Ulcers Using a Noncontact Near-Infrared Optical Imaging ApproachFull Text via DOI: 10.1089/wound.2017.0745 Web of Science: 000417110600001
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2015Noninvasive surface imaging of breast cancer in humans using a hand-held optical imagerFull Text via DOI: 10.1088/2057-1976/1/4/045001 Web of Science: 000422560200001
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2015Functional near-infrared imaging reconstruction based on spatiotemporal features: venous occlusion studiesFull Text via DOI: 10.1364/AO.54.000D82 Web of Science: 000353980900014
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2014Motor response investigation in individuals with cerebral palsy using near infrared spectroscopy: pilot studyFull Text via DOI: 10.1364/AO.53.000503 Web of Science: 000330172300026
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2013Resolution of a Gen-2 handheld optical imager: diffuse and fluorescence imaging studiesFull Text via DOI: 10.1364/AO.52.008060 Web of Science: 000327467200026
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2013Effect of Porosity on Photocatalytic Activity of Plasma-Sprayed TiO2 CoatingFull Text via DOI: 10.1007/s11666-013-9964-1 Web of Science: 000324241500012
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2013Functional connectivity in the brain in joint attention skills using near infrared spectroscopy and imagingFull Text via DOI: 10.1016/j.bbr.2013.04.028 Web of Science: 000321880400005
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2013Photocatalytic activity of spark plasma sintered TiO2-graphene nanoplatelet compositeFull Text via DOI: 10.1016/j.scriptamat.2013.01.012 Web of Science: 000317163800016
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2013Three-dimensional fluorescence tomography of human breast tissues in vivo using a hand-held optical imagerFull Text via DOI: 10.1088/0031-9155/58/5/1563 Web of Science: 000315191400025
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2013Fronto-temporal mapping and connectivity using NIRS for language-related paradigmsFull Text via DOI: 10.1016/j.jneuroling.2012.06.002 Web of Science: 000310413400011
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2012Hand-held optical imager (Gen-2): improved instrumentation and target detectabilityFull Text via DOI: 10.1117/1.JBO.17.8.081402 Web of Science: 000309696800012
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2012Hand-Held Optical Devices for Breast Cancer: Spectroscopy and 3-D Tomographic ImagingFull Text via DOI: 10.1109/JSTQE.2011.2170664 Web of Science: 000308113800006
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2012Gen-2 Hand-Held Optical Imager towards Cancer Imaging: Reflectance and Transillumination Phantom StudiesFull Text via DOI: 10.3390/s120201885 Web of Science: 000300720300041
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2011Frontal activation and connectivity using near-infrared spectroscopy: Verbal fluency language studyFull Text via DOI: 10.1016/j.brainresbull.2011.01.002 Web of Science: 000288885800001
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2011Frontal cortical connectivity and lateralisation of joint attention experience using near infrared spectroscopyFull Text via DOI: 10.1255/jnirs.921 Web of Science: 000292228600002
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2010Multi-projection fluorescence optical tomography using a handheld-probe-based optical imager: phantom studiesFull Text via DOI: 10.1364/AO.49.004343 Web of Science: 000280747700003
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2010Improved detection limits using a hand-held optical imager with coregistration capabilitiesFull Text via DOI: 10.1364/BOE.1.000126 Web of Science: 000208208100012
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2010Automated coregistered imaging using a hand-held probe-based optical imagerFull Text via DOI: 10.1063/1.3271019 Web of Science: 000275028400184
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2010Two-dimensional Fast surface imaging using a hand-held optical device: In-vitro and in-vivo fluorescence studiesFull Text via DOI: 10.1593/tlo.09157 Web of Science: 000278912600003
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2009Fluorescence tomographic imaging using a handheld-probe-based optical imager: extensive phantom studiesFull Text via DOI: 10.1364/AO.48.006408 Web of Science: 000272030800002
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2009Diffuse optical imaging of brain activation to joint attention experienceFull Text via DOI: 10.1016/j.bbr.2009.03.029 Web of Science: 000266695600006
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2008Three-dimensional fluorescence-enhanced optical tomography using a hand-held probe based imaging systemFull Text via DOI: 10.1118/1.2940603 Web of Science: 000257231700037
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2007Noise pre-filtering techniques in fluorescence-enhanced optical tomographyFull Text via DOI: 10.1364/OE.15.011285 Web of Science: 000249339800026
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2007Design and development of a hand-held optical probe toward fluorescence diagnostic imagingFull Text via DOI: 10.1117/1.2799193 Web of Science: 000251549600045
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2007Fluorescence-enhanced three-dimensional lifetime imaging: a phantom studyFull Text via DOI: 10.1088/0031-9155/52/14/009 Web of Science: 000247400000009
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2006Fluorescence-enhanced optical tomography of a large tissue phantom using point illumination geometriesFull Text via DOI: 10.1117/1.2338807 Web of Science: 000241162000041
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2005Fluorescence photon migration by the boundary element methodFull Text via DOI: 10.1016/j.jcp.2005.04.003 Web of Science: 000231265500005
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2005Detection of single and multiple targets in tissue phantoms with fluorescence-enhanced optical imaging: Feasibility studyFull Text via DOI: 10.1148/radiol.2343031725 Web of Science: 000227952600023
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2005Three-dimensional fluorescence lifetime tomographyFull Text via DOI: 10.1118/1.1861160 Web of Science: 000228659700018
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2005Tomographic fluorescence imaging in tissue phantoms: A novel reconstruction algorithm and imaging geometryFull Text via DOI: 10.1109/TMI.2004.839359 Web of Science: 000226697800001
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2004Diagnostic imaging of breast cancer using fluorescence-enhanced optical tomography: phantom studiesFull Text via DOI: 10.1117/1.1691027 Web of Science: 000221304400009
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2004Fluorescence-enhanced optical imaging of large phantoms using single and simultaneous dual point illumination geometriesFull Text via DOI: 10.1118/1.1639321 Web of Science: 000189023800003
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2003A comparison of exact and approximate adjoint sensitivities in fluorescence tomographyFull Text via DOI: 10.1109/TMI.2003.818165 Web of Science: 000185719100003
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2003Fluorescence-enhanced optical tomography using referenced measurements of heterogeneous mediaFull Text via DOI: 10.1109/TMI.2003.815072 Web of Science: 000184443900004
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2003Fluorescence-enhanced optical imaging in large tissue volumes using a gain-modulated ICCD cameraFull Text via DOI: 10.1088/0031-9155/48/12/303 Web of Science: 000184063200003
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2002Three-dimensional, Bayesian image reconstruction from sparse and noisy data sets: Near-infrared fluorescence tomographyFull Text via DOI: 10.1073/pnas.112217899 Web of Science: 000177042400006
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2000Neural networks in studies on oxidation behavior of laser surface engineered composite boride coatingsFull Text via DOI: 10.1016/S0169-4332(00)00279-8 Web of Science: 000088469700018
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2000Distribution and catalytic activity of eutectic salts in steam gasification of coalFull Text via DOI: 10.1021/ef990156o Web of Science: 000087139800007
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Book Chapter
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2014Near-infrared fluorescence imaging and spectroscopy in random media and tissues. 587-652.Full Text via DOI: 10.1201/b17289
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2003Near-Infrared Imaging with Fluorescent Contrast Agents. 445-528.Full Text via DOI: 10.1201/9780203912096-14
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2003Near-infrared Imaging With Fluorescent Contrast AgentsFull Text via DOI: 10.1201/9780203912096.ch14
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Conference
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2022Comparison of Oxygenated Flow Patterns in Diabetic Foot Ulcers Subjects and Controls in Response to Breath-HoldingFull Text via DOI: 10.1117/12.2610362 Web of Science: 000825431100006
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2021Noise removal techniques in smartphone based near infrared imaging of tissue oxygenation changes. 54.Full Text via DOI: 10.1117/12.2578816
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2019Oxygenation based perfusion assessment of diabetic foot ulcers using a breath-hold paradigmFull Text via DOI: 10.1117/12.2509917 Web of Science: 000492344300001
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2019Semi-automated machine learning approach to segment and register tissue oxygenation maps onto clinical images of woundsFull Text via DOI: 10.1117/12.2510065 Web of Science: 000492344300002
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2019Low-cost smartphone-based imaging device to detect subsurface tissue oxygenation of woundsFull Text via DOI: 10.1117/12.2510425 Web of Science: 000464093300012
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2018Tissue oxygenation changes in venous leg ulcersFull Text via DOI: 10.1364/TRANSLATIONAL.2018.JTu3A.7
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2016Wound size measurement of lower extremity ulcers using segmentation algorithmsFull Text via DOI: 10.1117/12.2212046 Web of Science: 000378218400039
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2015Non-contact optical imaging of healing and non-healing diabetic foot ulcersFull Text via DOI: 10.1117/12.2080716 Web of Science: 000353479900002
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2014Anatomical Co-Registration using Spatio-Temporal Features of a Non-contact Near-Infrared Optical ScannerFull Text via DOI: 10.1117/12.2037290 Web of Science: 000337064900005
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2014In-vivo Breast Imaging Using An Ultra-Portable Hand-Held Near-Infrared Optical Scanner (NIROS). bm3a.66.Full Text via DOI: 10.1364/biomed.2014.bm3a.66
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2014Spatio-Temporal Hemodynamic Imaging using a with Non-contact NIR scanner. bs3a.8.Full Text via DOI: 10.1364/biomed.2014.bs3a.8
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2013A Gen-2 Hand-Held Optical Imager: Phantom and preliminary in-vivo breast imaging studies. 103-104.Full Text via DOI: 10.1109/SBEC.2013.60 Web of Science: 000324751700052
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2013Implementation of a Novel, Integrative Approach for Optical 3D Positional Tracking towards Accurate Co-registered Imaging Using Hand-Held Optical Imagers. 81-82.Full Text via DOI: 10.1109/SBEC.2013.49 Web of Science: 000324751700041
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2013Investigation of Planning and Execution of Motor Skills in Healthy Adults using Simultaneous Near Infrared Spectroscopy and Kinematics Study. 135-136.Full Text via DOI: 10.1109/SBEC.2013.76 Web of Science: 000324751700068
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2013Phantom and in-vivo imaging using a Gen-2 hand-held optical imager: reflectance and transmission studiesFull Text via DOI: 10.1117/12.2004834 Web of Science: 000326708600012
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2013Portable Wide-Field Hand-Held NIR ScannerFull Text via DOI: 10.1117/12.2002704 Web of Science: 000337082600007
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2013Resolution Studies of a Hand-Held Optical ImagerFull Text via DOI: 10.1117/12.2002760 Web of Science: 000326708600058
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2013Simultaneous NIRS and kinematics study of planning and execution of motor skill task: towards cerebral palsy rehabilitationFull Text via DOI: 10.1117/12.2004746 Web of Science: 000324807200076
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2012Non-invasive optical imaging technology: Breast cancer imaging and functional brain mapping. 125.Full Text via DOI: 10.1109/PAHCE.2012.6233458
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2012Breast cancer imaging and tomography using a hand-held optical imagerFull Text via DOI: 10.1117/12.908528 Web of Science: 000302567700014
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2012Flexible gen-2 hand-held optical imager: Flat and curved phantom studiesFull Text via DOI: 10.1364/biomed.2012.bsu3a.74
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2012In vivo breast imaging using a gen-2 hand-held optical imagerFull Text via DOI: 10.1364/biomed.2012.btu3a.66
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2012Temporal mapping and connectivity using NIRS for language-related tasksFull Text via DOI: 10.1364/biomed.2012.btu3a.58
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20113D tomographic breast imaging in vivo using a hand-held optical imagerFull Text via DOI: 10.1117/12.874347 Web of Science: 000297631300051
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2011Joint attention studies in normal and autistic children using NIRSFull Text via DOI: 10.1117/12.874360 Web of Science: 000293947200068
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2011Temporal Mapping and Connectivity Using NIRS for Language-Related TasksFull Text via DOI: 10.1117/12.875256 Web of Science: 000293947200071
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2010Non-invasive Diagnostic Breast Imaging using a Hand-held Optical Imager. 158-161.Web of Science: 000391419900031
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2010Fast coregistered breast imaging in vivo using a hand-held optical imagerFull Text via DOI: 10.1117/12.842328 Web of Science: 000284396000010
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2010BRAIN CONNECTIVITY STUDY OF JOINT ATTENTION USING FREQUENCY-DOMAIN OPTICAL IMAGING TECHNIQUEFull Text via DOI: 10.1117/12.841504 Web of Science: 000283924300081
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2010Assessment of Tracking Devices towards Accurate Co-registration in a Hand-Held Optical Imager. btud58.Full Text via DOI: 10.1364/biomed.2010.btud58
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2010Improved Detection Limits using a Hand-held Optical Imager with Coregistration Capabilities. btud43.Full Text via DOI: 10.1364/biomed.2010.btud43
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2009Brain Connectivity Studies of Joint Attention Using Frequency-Domain Diffuse Optical Imaging. 7-8.Full Text via DOI: 10.1007/978-3-642-01697-4_4
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2009Clinical translation of a novel hand-held based optical imager: In vitro and in vivo studies. 3-4.Full Text via DOI: 10.1007/978-3-642-01697-4_2
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2009Fluorescence tomographic imaging using a hand-held optical imager: Extensive phantom studies. 1-2.Full Text via DOI: 10.1007/978-3-642-01697-4_1
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2009Multi-projection based fluorescence optical tomography using a hand-held probe based optical imagerFull Text via DOI: 10.1117/12.809935 Web of Science: 000285714800032
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2009Real-Time Coregistered Imaging using a Novel Hand-held Optical ImagerFull Text via DOI: 10.1117/12.809928 Web of Science: 000284395100024
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2009Brain Activation and Connectivity of Social Cognition using Diffuse Optical ImagingFull Text via DOI: 10.1117/12.809942 Web of Science: 000285713200063
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2009Noise filtration in fluorescence-enhanced optical tomography: breast phantom studies. 97-104.Full Text via DOI: 10.1080/17415970802083482 Web of Science: 000261195000008
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2008Fluorescence-enhanced imaging using a novel hand-held based optical imager: Phantom studies - art. no. 684809. 84809-84809.Full Text via DOI: 10.1117/12.764531 Web of Science: 000255549900003
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2008A hand-held probe-based optical imager with self co-registration facilitiesFull Text via DOI: 10.1364/biomed.2008.bmd49
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2008Joint attention studies using diffuse optical imagingFull Text via DOI: 10.1364/biomed.2008.bmd19
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2007Hand-held probe based optical imaging system towards breast cancer diagnosisFull Text via DOI: 10.1117/12.700637 Web of Science: 000245947500010
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2006A novel optical imager towards breast cancer diagnosis. 1989-1989.Full Text via DOI: 10.1118/1.2240150 Web of Science: 000238688500072
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2005Image reconstruction for diagnosis and prognosis of breast cancer using fluorescence measurements: Phantom studies. 203-209.Full Text via DOI: 10.1117/12.589209 Web of Science: 000229735700026
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2003Advances in 3-D frequency domain fluorescence tomography. 211-218.Full Text via DOI: 10.1117/12.478183 Web of Science: 000186054000024
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2003Hybrid approach to Bayesian image reconstruction. 591-599.Full Text via DOI: 10.1117/12.478184 Web of Science: 000186054000068
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2003Fluorescence-enhanced tomographic imaging in large phantoms using gain-modulated ICCD camera. 433-443.Full Text via DOI: 10.1117/12.476531 Web of Science: 000184498100056
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2002Experimental Frequency Domain Fluorescence Tomography. tud3.Full Text via DOI: 10.1364/bio.2002.tud3
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2002The Use of Referenced Measurements in Fluorescence-Enhanced Optical Tomography. mf5.Full Text via DOI: 10.1364/bio.2002.mf5
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Letter
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2015Diabetic wound imaging using a noncontact near-infrared scanner: A pilot study. 1158-1159.Full Text via DOI: 10.1177/1932296815590828
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Review
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2016Critical Review of Noninvasive Optical Technologies for Wound Imaging. 349-359.Full Text via DOI: 10.1089/wound.2015.0678 Web of Science: 000382628300004
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2016Near-Infrared Fluorescence-Enhanced Optical TomographyFull Text via DOI: 10.1155/2016/5040814 Web of Science: 000386269500001
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2015Optical imaging for breast cancer prescreening. 193-209.Full Text via DOI: 10.2147/BCTT.S51702 Web of Science: 000366129000001
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2009Hand-held based near-infrared optical imaging devices: A review. 495-509.Full Text via DOI: 10.1016/j.medengphy.2008.10.004 Web of Science: 000266963500001
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Works By Students
chaired theses and dissertations
- Chaudhary, Ujwal, Funtional Near Infrared Spectroscopy Study of Language, Joint Attention and Motor Skills 2013
- Gonzalez, Jean, Development and Testing of a Second Generation Hand-held Optical Imager 2012
- Hall, Michael A, Temporal Mapping and Connectivity using NIRS for Language Related Tasks 2012
- Erickson, Sarah J., Clinical Translation of a Novel Hand-held Optical Imager for Breast Cancer Diagnosis 2011
- Martinez, Sergio L, Performance Enhancement In Accuracy and Imaging Time of a Hand-Held Probe-Based Optical Imager 2011
Research
principal investigator on
- I-Corps: SPOT for Wound Care awarded by National Science Foundation 2021 - 2023
- Development of tissue oxygenation indices for acute wounds and diabetic foot ulcers using near-infrared imaging approach awarded by Diabetes & Digestive & Kidney Diseases 2020 - 2022
- Differentiate healing and non-healing diabetic foot ulcers using a portable, non-contact near-infrared optical scanner awarded by Diabetes & Digestive & Kidney Diseases 2018 - 2021
- Monitoring the effectiveness of radiation dermatitis treatment in cancer patients via tissue oxygenation measurements awarded by FIU Foundation 2018 - 2020
- Ultraportable wide-field NIR scanner awarded by FIU Office of Research and Economic Deve 2012 - 2014
- Coulter Translational Research Award in Biomedical Engin awarded by Wallace H. Coulter Foundation 2009 - 2012
- Function Brain Mapping of Autism Using Optical Imaging. awarded by University of Miami 2006 - 2012
- A Novel Hand-Held Based Optical Imager for Fluorescence Imaging of Breast Cancer. awarded by National Cancer Institute 2007 - 2011
- Subproject to Main Project OSRANbr 7396 (212100531): A Novel Hand-Held Based Optical Imager for Fluorescence Imaging of Breast Cancer. awarded by National Cancer Institute 2009 - 2010
- Hand Held Optical Probe for Fluorescence Imaging of Brea awarded by National Cancer Institute 2009 - 2010
- Diagnostic Mammography Using Real Time Co-Registering Novel Hand-Held Optical Imager. awarded by Florida Department of Health 2008 - 2009
- Bedside Optical Imaging of Epilepsy Patients. awarded by FIU Foundation 2006 - 2008
- Novel Breast Tissue Phantoms with Known Optical Properties. awarded by Imaging Diagnostic Systems 2006 - 2007
co-principal investigator on
- Biomedical Engineering Research Initiation Program. awarded by Wallace H. Coulter Foundation 2001 - 2018
- Clinical Translation of a Hand-held Optical Imager for Breast Imaging awarded by American Cancer Society 2011 - 2013
- Cancer Research in Memory of Barbara and Jerome Block. awarded by FIU Foundation 2008 - 2013
- Image Guided Intervention for Breast Cancer: Combined Hyperthermia and Chemotherapy with Reduced Cardiotoxicity. awarded by Florida Department of Health 2008 - 2009
subproject principal investigator on
- Hand-held Optical Imager for Breast Cancer Imaging awarded by National Cancer Institute 2011 - 2014
Videos
videos
Contact
full name
- Anuradha Godavarty
Identifiers
ORCID iD
- https://orcid.org/0000-0002-6094-5909 (confirmed)
visualizations
publication subject areas
- Behavioral Sciences
- Biochemistry & Molecular Biology
- Biotechnology & Applied Microbiology
- Chemistry
- Dermatology
- Electrochemistry
- Engineering
- Instruments & Instrumentation
- Linguistics
- Materials Science
- Mathematics
- Metallurgy & Metallurgical Engineering
- Neurosciences & Neurology
- Oncology
- Optics
- Physics
- Psychology
- Radiology, Nuclear Medicine & Medical Imaging
- Research & Experimental Medicine
- Science & Technology - Other Topics
- Spectroscopy