Jayant, Rahul Dev
Publications
selected publications
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Article
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2019Magnetically guided non-invasive CRISPR-Cas9/gRNA delivery across blood-brain barrier to eradicate latent HIV-1 infection. SCIENTIFIC REPORTS. 9.Full Text via DOI: 10.1038/s41598-019-40222-4 Web of Science: 000460627700016
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2018Withaferin A Suppresses Beta Amyloid in APP Expressing Cells: Studies for Tat and Cocaine Associated Neurological Dysfunctions. FRONTIERS IN AGING NEUROSCIENCE. 10.Full Text via DOI: 10.3389/fnagi.2018.00291 Web of Science: 000445757600001
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2018Multifunctional Nanotherapeutics for the Treatment of neuroAIDS in Drug Abusers. SCIENTIFIC REPORTS. 8.Full Text via DOI: 10.1038/s41598-018-31285-w Web of Science: 000442918300002
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2018A sensitive electrochemical immunosensor for label-free detection of Zika-virus protein. SCIENTIFIC REPORTS. 8.
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2018Recent advancements in nanoparticle based drug delivery for gastrointestinal disorders. EXPERT OPINION ON DRUG DELIVERY. 15:301-318.
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2018Recent treatment modalities for cardiovascular diseases with a focus on stem cells, aptamers, exosomes and nanomedicine. ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY. 46:S831-S840.Full Text via DOI: 10.1080/21691401.2018.1436555 Web of Science: 000457049400077
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2017Development of magneto-plasmonic nanoparticles for multimodal image-guided therapy to the brain. NANOSCALE. 9:764-773.
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2017Novel nanoformulation to mitigate co-effects of drugs of abuse and HIV-1 infection: towards the treatment of NeuroAIDS. JOURNAL OF NEUROVIROLOGY. 23:603-614.
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2016Advancements in nano-enabled therapeutics for neuroHIV management. INTERNATIONAL JOURNAL OF NANOMEDICINE. 11:4317-4325.
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2016Development of TIMP1 magnetic nanoformulation for regulation of synaptic plasticity in HIV-1 infection. INTERNATIONAL JOURNAL OF NANOMEDICINE. 11:4287-4298.
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2016Effect of Cocaine on HIV Infection and Inflammasome Gene Expression Profile in HIV Infected Macrophages. SCIENTIFIC REPORTS. 6.
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2016Electrochemical monitoring-on-chip (E-MoC) of HIV-infection in presence of cocaine and therapeutics. BIOSENSORS & BIOELECTRONICS. 86:426-431.
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2016Microglia-derived HIV Nef plus exosome impairment of the blood-brain barrier is treatable by nanomedicine-based delivery of Nef peptides. JOURNAL OF NEUROVIROLOGY. 22:129-139.
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2015Electrochemical sensing method for point-of-care cortisol detection in human immunodeficiency virus-infected patients. INTERNATIONAL JOURNAL OF NANOMEDICINE. 10:677-685.
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2015Sustained-release nanoART formulation for the treatment of neuroAIDS. INTERNATIONAL JOURNAL OF NANOMEDICINE. 10:1077-1093.
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2015Therapeutical Neurotargeting via Magnetic Nanocarrier: Implications to Opiate-Induced Neuropathogenesis and NeuroAIDS. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY. 11:1722-1733.
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2014HIV-1 Subtypes B and C Tat Differentially Impact Synaptic Plasticity Expression and Implicates HIV-Associated Neurocognitive Disorders. CURRENT HIV RESEARCH. 12:397-405.PMID: 25613138 Web of Science: 000351001100004
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Editorial Material
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2018Nanomedicine for neuroHIV/AIDS management. NANOMEDICINE.Full Text via DOI: 10.2217/nnm-2018-0005 Web of Science: 000432823900001
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Meeting Abstract
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2018Bio-distribution and bio-safety assessment of magneto-electric nanoparticles in non-human primate. JOURNAL OF NEUROVIROLOGY.Web of Science: 000434755400139
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2018Development of Cas9/gRNA based nano-formulation to eradicate latent HIV-1 infection in the brain. JOURNAL OF NEUROVIROLOGY.Web of Science: 000434755400322
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2018Intranasal Nanodelivery of Oxytocin to Treat Drug Addiction in HIV Patients using CRISPR Gene Editing. JOURNAL OF NEUROVIROLOGY.Web of Science: 000434755400134
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2018TEM-assisted evaluation of drug nano-carrier biodistribution in the brain. JOURNAL OF NEUROVIROLOGY.Web of Science: 000434755400211
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2018Withaferin A is a neuroprotective agent: Studies towards neurocognitive disorders. JOURNAL OF NEUROVIROLOGY.Web of Science: 000434755400296
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2018Bio-distribution and bio-safety assessment of magneto-electric nanoparticles in non-human primate. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S40-S41.Web of Science: 000429149100139
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2018Development of Cas9/gRNA based nano-formulation to eradicate latent HIV-1 infection in the brain. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S93-S93.Web of Science: 000429149100322
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2018Intranasal Nanodelivery of Oxytocin to Treat Drug Addiction in HIV Patients using CRISPR Gene Editing. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S39-S39.Web of Science: 000429149100134
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2018TEM-assisted evaluation of drug nano-carrier biodistribution in the brain. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S61-S61.Web of Science: 000429149100211
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2018Withaferin A is a neuroprotective agent: Studies towards neurocognitive disorders. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S86-S86.Web of Science: 000429149100296
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2017Development and Delivery of Intranasal Cas9/gRNA Aerosol Nanoformulation to Eradicate Latent HIV-1 in CNS. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S58-S59.Web of Science: 000414227700139
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2017Inflammasome Gene Expression and their role in HIV and Cocaine Induced Apoptosis. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S49-S50.Web of Science: 000414227700114
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2017MRI-assisted magnetically guided CNS delivery of magneto-electro nanoparticles in non-human primate. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S48-S48.Web of Science: 000414227700110
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2017Nanoelectroporation of magneto-electric nanoparticles as drug nano-carriers into the brain cells. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S66-S66.Web of Science: 000414227700158
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2017Withaferin A suppresses Beta amyloid in APP expressing cells: Studies for neurocognitive dysfunctions. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S43-S43.Web of Science: 000414227700098
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2016HIV-INFECTION AND SUBSTANCE OF ABUSE: OXIDATIVE STRESS INDUCES DOPAMINERGIC DYSFUNCTION AND NEUROPLASTICITY. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S47-S47.Web of Science: 000377566000121
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2015Characterization of on Demand Delivery of Fluorescent Magnetic Nanoparticle (MNP) Targeted Towards the Brain. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S97-S97.Web of Science: 000367554100107
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2015Effect of Magneto-electric nanoparticle on deep brain motor coordination activity. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S99-S100.Web of Science: 000367554100113
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2015In vitro & In-vivo Cytotoxic Evaluation of Magneto-Electric Nanoparticles for the CNS Delivery. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S81-S81.Web of Science: 000367554100064
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2015Sustained Release NanoART Formulation for the Treatment of NeuroAIDS. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. S77-S77.Web of Science: 000367554100055
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2014Electrochemical Immunosensor for the Detection of Cortisol. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. 27-28.Web of Science: 000333121600066
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2014Layer-by-Layer (LbL) Assembly of Anti HIV Drug for Sustained Release to Brain Using Magnetic Nanoparticle. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. 25-25.Web of Science: 000333121600060
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2014Novel magneto-electric nanodelivery of microRNA mimic across blood-brain barrier: Implications to cocaine modulation on HIV-associated neurocognitive disorders. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. 49-49.Web of Science: 000333121600122
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2014Role of HDAC2 and miR-485 in regulation of synaptic plasticity genes in HIV infection: Implication in HAND. JOURNAL OF NEUROIMMUNE PHARMACOLOGY. 6-6.Web of Science: 000333121600011
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Review
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2018Personalized nanomedicine for CNS diseases. DRUG DISCOVERY TODAY.Full Text via DOI: 10.1016/j.drudis.2017.11.010 Web of Science: 000434753100007
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2017Biomaterials and cells for neural tissue engineering: Current choices. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS. 1302-1315.
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2017Bioresponsive Injectable Hydrogels for On-demand Drug Release and Tissue Engineering. CURRENT PHARMACEUTICAL DESIGN. 3595-3602.
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2016Current status of non-viral gene therapy for CNS disorders. EXPERT OPINION ON DRUG DELIVERY. 1433-1445.
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2016Getting into the brain: Potential of nanotechnology in the management of NeuroAIDS. ADVANCED DRUG DELIVERY REVIEWS. 202-217.
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2016Nano-biosensors to detect beta-amyloid for Alzheimer's disease management. BIOSENSORS & BIOELECTRONICS. 273-287.
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2016Recent trends on hydrogel based drug delivery systems for infectious diseases. BIOMATERIALS SCIENCE. 1535-1553.
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2016Towards detection and diagnosis of Ebola virus disease at point-of-care. BIOSENSORS & BIOELECTRONICS. 254-272.
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2015Effect of human immunodeficiency virus on blood-brain barrier integrity and function: an update. FRONTIERS IN CELLULAR NEUROSCIENCE.
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2014The potential of magneto-electric nanocarriers for drug delivery. EXPERT OPINION ON DRUG DELIVERY. 1635-1646.
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Research
principal investigator on
- Intranasal Nanodelivery of Oxytocin to Treat Morphine Addiction in HIV Patients by Gene Editing awarded by National Institute on Drug Abuse 2017 - 2019
- Sustained Release of Nano-Medicine up to one month for the Treatment of HIV-1 infection awarded by Campbell Foundation 2017 - 2019
- Intranasal-CNS Delivery of ß-NAP Using Novel Simultaneous Spray Technology to Reverse Opiate & HIV-1 Induced Neurodegeneration awarded by FIU Foundation 2017 - 2019
investigator on
- Nanotechnology Based Gene Editing to Eradicate HIV Brain Reservoir in Drug Abusers awarded by National Institute on Drug Abuse 2016 - 2021
- Nano-delivery of methanandamide across BBB to block cannabinoid induced effects in HIV-1 infection awarded by National Institute on Drug Abuse 2017 - 2020
- Nano-delivery of methanandamide across BBB to block cannabinoid induced effects in HIV-1 infection awarded by National Institute on Drug Abuse 2015 - 2020
Contact
full name
- Rahul Dev Jayant
visualizations
Recent publications and grants in Scholars@FIU
research areas
- Biophysics
- Biotechnology & Applied Microbiology
- Chemistry
- Electrochemistry
- Engineering
- Geriatrics & Gerontology
- Immunology
- Infectious Diseases
- Materials Science
- Neurosciences & Neurology
- Pharmacology & Pharmacy
- Physics
- Science & Technology - Other Topics
- Virology