Kaftanovskaya, Elena

Kaftanovskaya, Elena
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Positions

Assistant Professor, Human and Molecular Genetics , Herbert Wertheim College of Medicine

Contact Info

ekaftano@fiu.edu

overview

Dr. Kaftanovskaya came to FIU from Baylor College of Medicine, Department of Obstetrics and Gynecology. At Baylor she conducted studies to define the hormonal and genetic factors responsible for reproductive organ development. Dr. Kaftanovskaya received her Ph.D. from the Institute of Cytology and Genetics, Russian Academy of Science, thereafter remaining as Instructor in Laboratory Developmental Genetics. She was involved in mammalian chromosome gene mapping and the analysis of chromosomal behavior in mouse stem cells. From 2001 - 2008 she was a Research Scientist at the Laboratory of Freshwater Fish Stocks, Bioscience and Biotechnology Center of Nagoya University, Japan. At Nagoya she developed a novel method of nuclear transplantation of adult somatic cells and embryonic cloning in small Japanese Medaka fish.

selected publications

Article
- 2020
  
  GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLOS GENETICS. 16.
  Full Text via DOI: 10.1371/journal.pgen.1008810 Web of Science: 000559723400013
- 2020
  
  Deletion of inositol polyphosphate 4-phosphatase type-II B affects spermatogenesis in mice. PLOS ONE. 15.
  Full Text via DOI: 10.1371/journal.pone.0233163 Web of Science: 000537496000052
- 2019
  
  Therapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis. FASEB JOURNAL. 33:12435-12446.
  Full Text via DOI: 10.1096/fj.201901046R Web of Science: 000507461600065
- 2017
  
  Human Relaxin Receptor Is Fully Functional in Humanized Mice and Is Activated by Small Molecule Agonist ML290
  Full Text via DOI: 10.1210/js.2017-00112 Web of Science: 000425346100016
- 2016
  
  Constitutive Notch Signaling Causes Abnormal Development of the Oviducts, Abnormal Angiogenesis, and Cyst Formation in Mouse Female Reproductive Tract. BIOLOGY OF REPRODUCTION. 94.
  Full Text via DOI: 10.1095/biolreprod.115.134569 PMID: 26843448 Web of Science: 000405110600009
- 2015
  
  Conditional Deletion of the Relaxin Receptor Gene in Cells of Smooth Muscle Lineage Affects Lower Reproductive Tract in Pregnant Mice. BIOLOGY OF REPRODUCTION. 92.
  Full Text via DOI: 10.1095/biolreprod.114.127209 PMID: 25715795 Web of Science: 000352712200009
- 2015
  
  Genetic ablation of androgen receptor signaling in fetal Leydig cell lineage affects Leydig cell functions in adult testis. FASEB JOURNAL. 29:2327-2337.
  Full Text via DOI: 10.1096/fj.14-263632 PMID: 25713029 Web of Science: 000355209500011
- 2015
  
  HIV Subtypes B and C gp120 and Methamphetamine Interaction: Dopaminergic System Implicates Differential Neuronal Toxicity. SCIENTIFIC REPORTS. 5.
  Full Text via DOI: 10.1038/srep11130 PMID: 26057350 Web of Science: 000356087900001
- 2015
  
  Preparation and characterization of anti-HIV nanodrug targeted to microfold cell of gut-associated lymphoid tissue. INTERNATIONAL JOURNAL OF NANOMEDICINE. 10:5819-5835.
  Full Text via DOI: 10.2147/IJN.S68348 PMID: 26425084 Web of Science: 000361620300001
- 2014
  
  beta-Amyloid(1-42), HIV-1(Ba-L) (Clade B) Infection and Drugs of Abuse Induced Degeneration in Human Neuronal Cells and Protective Effects of Ashwagandha (Withania somnifera) and Its Constituent Withanolide A. PLOS ONE. 9.
  Full Text via DOI: 10.1371/journal.pone.0112818 PMID: 25415340 Web of Science: 000346906600017
- 2013
  
  Mechanisms of INSL3 signaling in male reproductive organs
- 2013
  
  Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis. JOURNAL OF PATHOLOGY. 230:39-47.
  Full Text via DOI: 10.1002/path.4161 PMID: 23288785 Web of Science: 000317434000006
- 2012
  
  Cryptorchidism in Mice with an Androgen Receptor Ablation in Gubernaculum Testis. MOLECULAR ENDOCRINOLOGY. 26:598-607.
  Full Text via DOI: 10.1210/me.2011-1283 PMID: 22322597 Web of Science: 000302139800007
- 2011
  
  Suppression of Insulin-Like3 Receptor Reveals the Role of beta-Catenin and Notch Signaling in Gubernaculum Development. MOLECULAR ENDOCRINOLOGY. 25:170-183.
  Full Text via DOI: 10.1210/me.2010-0330 PMID: 21147849 Web of Science: 000285745800014
- 2011
  
  Uterine Cysts in Female Mice Deficient for Caveolin-1 and Insulin-Like 3 Receptor RXFP2. ENDOCRINOLOGY. 152:2474-2482.
  Full Text via DOI: 10.1210/en.2010-1015 PMID: 21467199 Web of Science: 000290788500034
- 2010
  
  Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis. ENDOCRINE-RELATED CANCER. 17:1021-1033.
  Full Text via DOI: 10.1677/ERC-10-0073 PMID: 20861284 Web of Science: 000284490000021
Meeting Abstract
- 2010
  
  Hormonal Regulation of Testicular Descent. BIOLOGY OF REPRODUCTION. 55-55.
  Web of Science: 000284381300017
- 2010
  
  INSL3/RXFP2 AND ANDROGEN SIGNALING IN TESTICULAR DESCENT. JOURNAL OF ANDROLOGY. 48-49.
  Web of Science: 000275920400043

full name

Elena Kaftanovskaya

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