Wei-Chiang Lin
- Associate Professor, Biomedical Engineering , College of Engineering and Computing
Publications
selected publications
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Article
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2020Advances in imaging and analysis of 4 fluorescent components through the rat cortical column. JOURNAL OF NEUROSCIENCE METHODS. 341.Full Text via DOI: 10.1016/j.jneumeth.2020.108792 Web of Science: 000546302200001
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2018Histological Characterization of the Irritative Zones in Focal Cortical Dysplasia Using a Preclinical Rat Model. FRONTIERS IN CELLULAR NEUROSCIENCE. 12.Full Text via DOI: 10.3389/fncel.2018.00052 Web of Science: 000432606600001
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2018Effects of Closed Endotracheal Suctioning on Systemic and Cerebral Oxygenation and Hemodynamics in Children. PEDIATRIC CRITICAL CARE MEDICINE. 19:E23-E30.
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2018Heart Rate Variability in Children Following Drowning InjuryFull Text via DOI: 10.4103/ijccm.IJCCM_120_16 Web of Science: 000423340500014
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2017Quantitative assessment of hemodynamic and structural characteristics of in vivo brain tissue using total diffuse reflectance spectrum measured in a non-contact fashion. BIOMEDICAL OPTICS EXPRESS. 8:78-103.
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2016Dysfunction of Neurovascular/Metabolic Coupling in Chronic Focal Epilepsy. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. 63:97-110.Full Text via DOI: 10.1109/TBME.2015.2461496 Web of Science: 000369311700010
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2016Intraoperative optical mapping of epileptogenic cortices during non-ictal periods in pediatric patients. NEUROIMAGE-CLINICAL. 11:423-434.
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2015Peptide modified polymer poly (glycerol- dodecanedioate co-fumarate) for efficient control of motor neuron differentiation. BIOMEDICAL MATERIALS. 10.
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2013Optical ATP biosensor for extracellular ATP measurement. BIOSENSORS & BIOELECTRONICS. 43.Full Text via DOI: 10.1016/j.bios.2012.12.027 Web of Science: 000316525300058
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2013Evaluating and improving the quality of time-dependent, diffuse reflectance spectroscopic signals measured from in vivo brain during craniotomy. MEDICAL ENGINEERING & PHYSICS. 35:1551-1557.
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2013In vivo detection of epileptic brain tissue using static fluorescence and diffuse reflectance spectroscopy. JOURNAL OF BIOMEDICAL OPTICS. 18.
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2011Estimation of regional hemoglobin concentration in biological tissues using diffuse reflectance spectroscopy with a novel spectral interpretation algorithm. PHYSICS IN MEDICINE AND BIOLOGY. 56:3985-4000.
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2011In vivo optical properties of cortical tubers in children with tuberous sclerosis complex (TSC): a preliminary investigation. EPILEPSIA. 52:1699-1704.
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2011Spectral-profile-based algorithm for hemoglobin oxygen saturation determination from diffuse reflectance spectra. BIOMEDICAL OPTICS EXPRESS. 2:1082-1096.
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2010Diffuse reflectance spectroscopy for in vivo pediatric brain tumor detection. JOURNAL OF BIOMEDICAL OPTICS. 15.
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2010In vivo characterization of myocardial infarction using fluorescence and diffuse reflectance spectroscopy. JOURNAL OF BIOMEDICAL OPTICS. 15.
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2009Optical spectroscopy for in-vitro differentiation of pediatric neoplastic and epileptogenic brain lesions. JOURNAL OF BIOMEDICAL OPTICS. 14.
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2008Effects of probe contact pressure on in vivo optical spectroscopy. OPTICS EXPRESS. 16:4250-4262.
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2007A probability-based spectroscopic diagnostic algorithm for simultaneous discrimination of brain tumor and tumor margins from normal brain tissue. APPLIED SPECTROSCOPY. 61:548-557.
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2006In vitro determination of normal and neoplastic human brain tissue optical properties using inverse adding-doubling. PHYSICS IN MEDICINE AND BIOLOGY. 51:2011-2027.
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2005INTRAOPERATIVE OPTICAL SPECTROSCOPY IDENTIFIES INFILTRATING GLIOMA MARGINS WITH HIGH SENSITIVITY. NEUROSURGERY. 57:382-390.
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2004In vivoassessment of thermal damage in the liver using optical spectroscopyFull Text via DOI: 10.1117/1.1779627
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2001Intraoperative application of optical spectroscopy in the presence of bloodFull Text via DOI: 10.1109/2944.983305
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2001Brain tissue characterization using Spectral Imaging: A potential clinical toolFull Text via DOI: 10.1117/12.432484
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2000Brain tumor demarcation using optical spectroscopy; An in vitro studyFull Text via DOI: 10.1117/1.429989
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1996Dynamics of tissue optics during laser heating of turbid mediaFull Text via DOI: 10.1364/AO.35.003413
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1995Nonlinear optical behavior of ocular tissue during laser irradiationFull Text via DOI: 10.1364/AO.34.007979
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Conference
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2008Optical characterization of myocardial infarction: An in vivo studyFull Text via DOI: 10.1364/biomed.2008.btuf41
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2005Decline in NAD(P)H autofluorescence precedes apoptotic cell death from chemotherapyFull Text via DOI: 10.1117/12.630711
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2003Feedback control of liver thermotherapy using optical spectroscopy. 201-212.Full Text via DOI: 10.1117/12.479803
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2001Accelerated stressing and degradation mechanisms for Si-based photo-emitters. 200-205.Full Text via DOI: 10.1109/RELPHY.2001.922902
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1994Dynamics of tissue reflectance and transmittance during laser irradiation. 296-303.Full Text via DOI: 10.1117/12.182947
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Editorial Material
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2013The Role of Complementary and Alternative Medicine in Regenerative Medicine. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE.Full Text via DOI: 10.1155/2013/420458 Web of Science: 000325022700001
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Meeting Abstract
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2010Immunoparalysis: a new approach for its early detection and resolution. FASEB JOURNAL.Web of Science: 000208675502015
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Other Scholarly Work
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Proceedings Paper
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2013Optical Spectroscopy for In Vivo Estimation of Hemodynamics and Structural Properties of the Brain. 29TH SOUTHERN BIOMEDICAL ENGINEERING CONFERENCE (SBEC 2013). 107-108.Full Text via DOI: 10.1109/SBEC.2013.62 Web of Science: 000324751700054
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2012Low-frequency pathophysiological characteristics of pediatric epileptic cortex during the interictal period detected using a dual-wavelength imaging system. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.911031 Web of Science: 000304813000028
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2010Determination of in vivo Blood Oxygen Saturation and Blood Volume Fraction Using Diffuse Reflectance Spectroscopy. 26TH SOUTHERN BIOMEDICAL ENGINEERING CONFERENCE: SBEC 2010. 336-339.Web of Science: 000307744700086
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2010In vivo Characterization of Epileptic Tissue with Time-Dependent, Diffuse Reflectance Spectroscopy. 26TH SOUTHERN BIOMEDICAL ENGINEERING CONFERENCE: SBEC 2010.Web of Science: 000307744700028
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2008Time-dependent diffuse reflectance spectroscopy for in vivo characterization of pediatric epileptogenic brain lesions. PHOTONIC THERAPEUTICS AND DIAGNOSTICS IV.Full Text via DOI: 10.1117/12.763407 Web of Science: 000255314100045
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2007In vivo optical characterization of pediatric epileptogenic lesions. PHOTONIC THERAPEUTICS AND DIAGNOSTICS III.Full Text via DOI: 10.1117/12.700717 Web of Science: 000246515600044
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2007In-vivo optical detection of brain tumor and tumor margin: a combined autofluoreseence and diffuse reflectance spectroscopic study. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS V.Full Text via DOI: 10.1117/12.724875 Web of Science: 000245947500007
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Review
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2006Neuro-oncological applications of optical spectroscopy. 231-238.Full Text via DOI: 10.1177/153303460600500306
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chaired theses and dissertations
- Le, Anh Van, The Development of a Novel Polymer Based System for Gene Delivery 2015
- Song, Yinchen, Intraoperative Guidance for Pediatric Brain Surgery based on Optical Techniques 2015
- Dai, Xizi, Fiber Scaffolds of Poly (glycerol-dodecanedioate) and its Derivative via Electrospinning for Neural Tissue Engineering 2015
- Yadav, Nitin, In Vivo characterization of Epileptic Tissue with Optical Spectroscopy 2012
- Chen, Po-Ching, In Vivo Tissue Diagnosis for Myocardial Infarction Using Optical Spectroscopy with Novel Spectral Interpretation Algorithms 2011
- Fernald, Bradley A., Mathematical method for physiological interpretation of diffuse reflectance spectroscopic signals 2008
Research
principal investigator on
- The Biomedical Engineering Lecture Series Endowment. awarded by Wallace H. Coulter Foundation 2005 - 2018
- Biomedical Engineering Distinguished Professorship in Bioinstrumentation and Biomeasurement awarded by Wallace H. Coulter Foundation 2004 - 2018
- Biomedical Engineering Excellence Scholarship Fund awarded by Wallace H. Coulter Foundation 2001 - 2018
- Biomedical Engineering Research Initiation Program. awarded by Wallace H. Coulter Foundation 2001 - 2018
- Graduate Fellowship in Biomedical Engineering Fund awarded by Wallace H. Coulter Foundation 2001 - 2018
- Multimodal Neuromonitoring and Neuroprotection in Critically Ill Children awarded by U.S. Army 2013 - 2018
- The Young Inventor Program Endowment awarded by Wallace H. Coulter Foundation 2004 - 2017
- Biomedical Engineering Excellence Fund. awarded by Wallace H. Coulter Foundation 2001 - 2017
- Cardiovascular Engineering Center Fund awarded by Wallace H. Coulter Foundation 2001 - 2017
- The Norman R. Weldon Biomedical Engineering Fellowship(s) Endowment awarded by Norman R. Weldon 2001 - 2017
- Smart Intraoperative Guidance for Pediatric Brain Tumor Surgery awarded by National Institutes of Health 2013 - 2017
- Hand-held Optical Imager for Breast Cancer Imaging awarded by National Institutes of Health 2011 - 2014
- Novel Optical Guidance for Surgical Resection of Pediatric Neoplastic and Epileptogenic Brain Lesions awarded by Nicklaus Children's Hospital 2010 - 2013
- DOD II: Multimodal Neuromonitoring and Neuroprotection in Critically Ill Children awarded by Nicklaus Children's Hospital 2010 - 2012
- Optimizing Pediatric Brain Tumor Surgery through Optical Spectoscopy to Enhance Survival and Quality of Life. awarded by Nicklaus Children's Hospital 2007 - 2011
- In Vivo Differentiation of Normal, Stunned, Hibernating, and Scarred Myocardium Using Optical Spectroscopy. awarded by American Heart Association 2006 - 2010
co-principal investigator on
- Cancer Research in Memory of Barbara and Jerome Block. awarded by FIU Foundation 2008 - 2013
- 25th Southern Biomedical Engineering Conference. awarded by National Science Foundation 2009 - 2010
- Image Guided Intervention for Breast Cancer: Combined Hyperthermia and Chemotherapy with Reduced Cardiotoxicity. awarded by Florida Department of Health 2008 - 2009
Teaching
teaching activities
- BME1008-U01: Introduction to Biomedical Engineering Fall Term 2019
- BME1008-U01: Introduction to Biomedical Engineering Spring Term 2019
- BME4531-U01: Medical Imaging Spring Term 2019
- BME5505-RXAX: Engineering Foundation of Medical Imaging Instrument Spring Term 2019
- BME5505-U01: Engineering Foundation of Medical Imaging Instrument Spring Term 2019
Contact
full name
- Wei-Chiang Lin
visualizations
Recent publications and grants in Scholars@FIU
publication subject areas
- Biochemistry & Molecular Biology
- Biophysics
- Biotechnology & Applied Microbiology
- Cell Biology
- Chemistry
- Electrochemistry
- Engineering
- General & Internal Medicine
- Instruments & Instrumentation
- Integrative & Complementary Medicine
- Life Sciences & Biomedicine - Other Topics
- Materials Science
- Medical Laboratory Technology
- Neurosciences & Neurology
- Optics
- Pediatrics
- Radiology, Nuclear Medicine & Medical Imaging
- Science & Technology - Other Topics
- Spectroscopy
- Surgery