Nefzi, Adel

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  • Dr. Nefzi obtained a PhD in organic chemistry in 1995 from the University of Lausanne, Switzerland. His lab research interests are in the broadly defined fields of organic synthesis and medicinal chemistry. His group efforts over the past twenty-five years have been focused on the design and the diversity-oriented synthesis of low molecular weight acyclic and heterocyclic natural product-like and existing drug-like combinatorial libraries from modified peptides for the use in therapeutic applications. The large numbers of chemical libraries of linear and cyclic peptides, non-peptide oligomers, peptidomimetics, small-molecules, and natural product-like organic molecules provide for an exponential increase in screening efficiencies, rich initial SAR, and a unique chemical space while maintaining critical drug like chemical properties. As evidenced by his group publication’s record, the synthetic libraries developed have impacted numerous fields of human health, including cancer, inflammation, pain, diabetes, CNS disorders, antimalarial, and bacterial resistance. Dr. Nefzi research has been supported by the National Institute of Health (NIH), the National Institute of Allergy and Infectious Diseases (NIAID), the National Institute on Drug Abuse (NIDA), the National Cancer Institute (NCI), the National Institute of Aging (NIA) and the National Science Foundation (NSF).

selected publications

full name

  • Adel Nefzi


Recent publications and grants in Scholars@FIU