Overview
overview
- Dr. Noriega is a Professor of Biological Sciences. Noriega's research has been funded by NIH's RO1s for more than 15 years. Currently, the main focus of his research program is the study of the nutritional regulation of synthesis of juvenile hormone, a molecule that regulates development, reproduction and behavior in the Aedes aegypti mosquito, the vector of Dengue and Yellow fever.
research interests
- Physiology, biochemistry, molecular biology, genomics and proteomics to study mosquito's physiological processes such as digestion, activity of the endocrine system and hormonal and nutritional regulation of gene expression.
Scholarly & Creative Works
selected publications
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Article
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2022Sexual dimorphism of diapause regulation in the hemipteran bug Pyrrhocoris apterusFull Text via DOI: 10.1016/j.ibmb.2022.103721 Web of Science: 000780386200006
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2022The insect somatostatin pathway gates vitellogenesis progression during reproductive maturation and the post-mating responseFull Text via DOI: 10.1038/s41467-022-28592-2 Web of Science: 000780120200012
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2021Epoxidation of juvenile hormone was a key innovation improving insect reproductive fitnessFull Text via DOI: 10.1073/pnas.2109381118 Web of Science: 000720928400015
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2021Juvenile hormone mediates lipid storage in the oocytes of Dipetalogaster maximaFull Text via DOI: 10.1016/j.ibmb.2020.103499 Web of Science: 000658512600011
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2021Following de novo triglyceride dynamics in ovaries of Aedes aegypti during the previtellogenic stageFull Text via DOI: 10.1038/s41598-021-89025-6 Web of Science: 000656459200017
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2020The juvenile hormone described in Rhodnius prolixus by Wigglesworth is juvenile hormone III skipped bisepoxideFull Text via DOI: 10.1038/s41598-020-59495-1 Web of Science: 000563080600004
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2019Inhibition of juvenile hormone synthesis in mosquitoes by the methylation inhibitor 3-deazaneplanocin A (DZNep)Full Text via DOI: 10.1016/j.ibmb.2019.103183 Web of Science: 000487571000011
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2019Ecdysis triggering hormone receptors regulate male courtship behavior via antennal lobe interneurons in DrosophilaFull Text via DOI: 10.1016/j.ygcen.2018.12.003 Web of Science: 000470948400009
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2019Three dimensional secondary ion mass spectrometry imaging (3D-SIMS) of Aedes aegypti ovarian folliclesFull Text via DOI: 10.1039/c8ja00425k Web of Science: 000485195500007
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2019Juvenile hormone controls ovarian development in female Anopheles albimanus mosquitoesFull Text via DOI: 10.1038/s41598-019-38631-6 Web of Science: 000458619600126
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2018JH biosynthesis and hemolymph titers in adult male Aedes aegypti mosquitoesFull Text via DOI: 10.1016/j.ibmb.2018.02.005 Web of Science: 000440265600002
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2017MicroRNAs regulate the sesquiterpenoid hormonal pathway in Drosophila and other arthropodsFull Text via DOI: 10.1098/rspb.2017.1827 Web of Science: 000418463000008
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2017How micronutrients influence the physiology of mosquitoesFull Text via DOI: 10.1016/j.cois.2017.07.002 Web of Science: 000417019800018
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2017Hormonal Signaling Cascade during an Early-Adult Critical Period Required for Courtship Memory Retention in DrosophilaFull Text via DOI: 10.1016/j.cub.2017.08.017 Web of Science: 000411581800026
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2017Endocrine network essential for reproductive success in Drosophila melanogasterFull Text via DOI: 10.1073/pnas.1620760114 Web of Science: 000400818400015
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2017Allatotropin: A pleiotropic neuropeptide that elicits mosquito immune responsesFull Text via DOI: 10.1371/journal.pone.0175759 Web of Science: 000399875900045
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2016Fast, ultra-trace detection of juvenile hormone III from mosquitoes using mass spectrometryFull Text via DOI: 10.1016/j.talanta.2016.06.041 Web of Science: 000381322000050
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2016Allatostatin-C antagonizes the synergistic myostimulatory effect of allatotropin and serotonin in Rhodnius prolixus (Stal)Full Text via DOI: 10.1016/j.ygcen.2016.05.009 Web of Science: 000378462800001
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2015Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infectionFull Text via DOI: 10.1073/pnas.1506226112 Web of Science: 000365988900059
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2015Negative Feedbacks by Isoprenoids on a Mevalonate Kinase Expressed in the Corpora Allata of MosquitoesFull Text via DOI: 10.1371/journal.pone.0143107 Web of Science: 000367628500091
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201520-hydroxyecdysone stimulation of juvenile hormone biosynthesis by the mosquito corpora allataFull Text via DOI: 10.1016/j.ibmb.2015.08.001 Web of Science: 000361402900011
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2015A corpora allata farnesyl diphosphate synthase in mosquitoes displaying a metal ion dependent substrate specificityFull Text via DOI: 10.1016/j.ibmb.2015.07.010 Web of Science: 000361402900005
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2015Allatotropin Modulates Myostimulatory and Cardioacceleratory Activities in Rhodnius prolixus (Stal)Full Text via DOI: 10.1371/journal.pone.0124131 Web of Science: 000353212600050
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2015Methyl Farnesoate Plays a Dual Role in Regulating Drosophila MetamorphosisFull Text via DOI: 10.1371/journal.pgen.1005038 Web of Science: 000352197100030
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2015Coordinated changes in JH biosynthesis and JH hemolymph titers in Aedes aegypti mosquitoesFull Text via DOI: 10.1016/j.jinsphys.2014.11.003 Web of Science: 000351323100003
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2014Ecdysis triggering hormone ensures proper timing of juvenile hormone biosynthesis in pharate adult mosquitoesFull Text via DOI: 10.1016/j.ibmb.2014.09.006 Web of Science: 000344440500011
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2014Sublethal metal stress response of larvae of Aedes aegyptiFull Text via DOI: 10.1111/phen.12054 Web of Science: 000336381400004
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2014Starvation Increases Insulin Sensitivity and Reduces Juvenile Hormone Synthesis in MosquitoesFull Text via DOI: 10.1371/journal.pone.0086183 Web of Science: 000330570000027
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2013Allatotropin: An Ancestral Myotropic Neuropeptide Involved in FeedingFull Text via DOI: 10.1371/journal.pone.0077520 Web of Science: 000325894100078
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2013Farnesyl Phosphatase, a Corpora allata Enzyme Involved in Juvenile Hormone Biosynthesis in Aedes aegyptiFull Text via DOI: 10.1371/journal.pone.0071967 Web of Science: 000324465000236
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2013Aldehyde dehydrogenase 3 converts farnesal into farnesoic acid in the corpora allata of mosquitoesFull Text via DOI: 10.1016/j.ibmb.2013.04.002 Web of Science: 000322561700006
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2013Aedes aegypti pharate 1st instar quiescence: A case for anticipatory reproductive plasticityFull Text via DOI: 10.1016/j.jinsphys.2012.12.007 Web of Science: 000316776100010
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2013FUNCTIONAL ANALYSIS OF A MOSQUITO SHORT-CHAIN DEHYDROGENASE CLUSTERFull Text via DOI: 10.1002/arch.21078 Web of Science: 000313244200005
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2012Characterization of an isopentenyl diphosphate isomerase involved in the juvenile hormone pathway in Aedes aegyptiFull Text via DOI: 10.1016/j.ibmb.2012.07.002 Web of Science: 000309620400003
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2012A Quantitative Assay for the Juvenile Hormones and Their Precursors Using Fluorescent TagsFull Text via DOI: 10.1371/journal.pone.0043784 Web of Science: 000308286300089
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2012The fate of follicles after a blood meal is dependent on previtellogenic nutrition and juvenile hormone in Aedes aegyptiFull Text via DOI: 10.1016/j.jinsphys.2012.05.005 Web of Science: 000306767700018
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2012Aedes aegypti pharate 1st instar quiescence affects larval fitness and metal toleranceFull Text via DOI: 10.1016/j.jinsphys.2012.03.005 Web of Science: 000305106200008
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2012Functional characterization of an allatotropin receptor expressed in the corpora allata of mosquitoesFull Text via DOI: 10.1016/j.peptides.2011.07.025 Web of Science: 000302851500027
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2011Thermal Adaptation and Diversity in Tropical Ecosystems: Evidence from Cicadas (Hemiptera, Cicadidae)Full Text via DOI: 10.1371/journal.pone.0029368 Web of Science: 000300677000029
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2011Nutrient limitation results in juvenile hormone-mediated resorption of previtellogenic ovarian follicles in mosquitoesFull Text via DOI: 10.1016/j.jinsphys.2011.06.002 Web of Science: 000295441700014
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2010Rapid direct analysis in real time (DART) mass spectrometric detection of juvenile hormone III and its terpene precursorsFull Text via DOI: 10.1007/s00216-010-4269-4 Web of Science: 000284542300027
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2010Allatostatin-C receptors in mosquitoesFull Text via DOI: 10.1016/j.peptides.2009.04.013 Web of Science: 000275994100011
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2009NADP(+)-dependent farnesol dehydrogenase, a corpora allata enzyme involved in juvenile hormone synthesisFull Text via DOI: 10.1073/pnas.0909938106 Web of Science: 000272795300017
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2007Role of juvenile hormone and allatotropin on nutrient allocation, ovarian development and survivorship in mosquitoesFull Text via DOI: 10.1016/j.jinsphys.2006.08.009 Web of Science: 000245483100004
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2006Comparative genomics of insect juvenile hormone biosynthesisFull Text via DOI: 10.1016/j.ibmb.2006.01.013 Web of Science: 000236755000015
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2006Effects of larval nutrition on the endocrinology of mosquito egg developmentFull Text via DOI: 10.1242/jeb.02026 Web of Science: 000236042200011
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2005Immunostaining for allatotropin and allatostatin-A and -C in the mosquitoes Aedes aegypti and Anopheles albimanusFull Text via DOI: 10.1007/s00441-005-1133-5 Web of Science: 000230317000011
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2004Convergence and parallelism among cicadas of Argentina and the southwestern United States (Hemiptera : Cicadoidea)Full Text via DOI: 10.1111/j.1095-8312.2004.00394.x Web of Science: 000224662500012
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2004Nutritional regulation of JH synthesis: a mechanism to control reproductive maturation in mosquitoes?Full Text via DOI: 10.1016/j.ibmb.2004.03.021 Web of Science: 000222953700012
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2004Reduced juvenile hormone synthesis in mosquitoes with low teneral reserves reduces ovarian previtellogenic development in Aedes aegyptiFull Text via DOI: 10.1242/jeb.01093 Web of Science: 000223090300025
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1994Dietary control of late trypsin gene transcription in Aedes aegyptiFull Text via DOI: 10.1016/0965-1748(94)90099-X
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1993A comparison of three methods for isolating RNA from mosquitoesFull Text via DOI: 10.1111/j.1365-2583.1993.tb00121.x
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Book Chapter
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2016Chapter Four The Role of Juvenile Hormone in Mosquito Development and Reproduction. 93-113.Full Text via DOI: 10.1016/bs.aiip.2016.04.005
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2016The Role of Juvenile Hormone in Mosquito Development and Reproduction. 93-113.Full Text via DOI: 10.1016/bs.aiip.2016.04.005 Web of Science: 000383859500005
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Conference
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2016Metabolic analysis of the juvenile hormone synthesis pathways in mosquitoesFull Text via DOI: 10.1603/ice.2016.91917
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2013A METABOLOMIC ANALYSIS OF JH SYNTHESIS IN AEDES AEGYPTI. 408-408.Web of Science: 000335056200025
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2013NUTRITION, JUVENILE HORMONE SYNTHESIS AND REPRODUCTION IN MOSQUITOES. 409-410.Web of Science: 000335056200030
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2013
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Other Scholarly Work
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2021Following de novo triglyceride dynamics in ovaries of Aedes aegypti during the previtellogenic stage (vol 11, 9636, 2021)Full Text via DOI: 10.1038/s41598-021-95696-y Web of Science: 000684439500002
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2018Editorial overview: Molecular physiology: from omics data encyclopedia to physiology 'short stories'. VI-VIII.Full Text via DOI: 10.1016/j.cois.2018.08.004 Web of Science: 000452866500002
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2016Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection (vol 112, pg 14936, 2015). E1415-E1416.Full Text via DOI: 10.1073/pnas.1600205113 Web of Science: 000372013300016
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Preprint
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2021Bioactive isoprenoids guide migrating germ cells to the embryonic gonadFull Text via DOI: 10.1101/2021.09.30.462471
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Review
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2020Approaches and Tools to Study the Roles of Juvenile Hormones in Controlling Insect BiologyFull Text via DOI: 10.3390/insects11120858 Web of Science: 000602170400001
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2019Mosquito adaptations to hematophagia impact pathogen transmission. 21-26.Full Text via DOI: 10.1016/j.cois.2019.02.002 Web of Science: 000483374000007
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2018Omics approaches to study juvenile hormone synthesis. 49-55.Full Text via DOI: 10.1016/j.cois.2018.05.013 Web of Science: 000452866500010
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2008Cyanobacterial toxins as allelochemicals with potential applications as algaecides, herbicides and insecticides. 117-146.Full Text via DOI: 10.3390/md20080007 Web of Science: 000257202100004
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2008Cyanobacterial toxins as allelochemicals with potential applications as algaecides, herbicides and insecticides. 117-146.Full Text via DOI: 10.3390/md6020117
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Works By Students
chaired theses and dissertations
- Nyati, Pratik, Characterization of Juvenile Hormone Biosynthetic Enzymes in the Mosquito, Aedes aegypti 2014
- Berry, Gerald A, Mosquito Larvicides from Cyanobacteria 2014
- Areiza, Maria, Ecdysis Triggering Hormone and its Role in Juvenile Hormone Synthesis in the Yellow-fever Mosquito, Aedes aegypti 2014
- Perez, Mario H., Aedes aegypti Pharate First Instar Aseasonal Quiescence Cues Anticipatory Plasticity with Implications for Urban Vector Ecology and Control 2013
- clifton, Mark E, The Endocrine Basis for Reproductive Life-history Trade-offs during the Previtellogenic Resting Stage in the Yellow Fever Mosquito, Aedes aegypti 2012
advised honors theses
- Correa, Stefano, Sugar Feeding Affects the Male Contribution in Reproduction in Aedes Aegypti 2013
- Cole, Tatiana Rosa, The Application of Fluorescent Nanocrystals to Study the Distribution of Neuropeptides in the Aedes Aegypti Mosquito 2006
Research
principal investigator on
- How can mosquitoes develop and reproduce in the complete absence of juvenile hormone? awarded by Allergy and Infectious Diseases 2022 - 2024
- Regulation of juvenile hormone titers in mosquitoes awarded by Allergy and Infectious Diseases 2015 - 2022
- Regulation of Juvenile Hormone Titers in Mosquitoes awarded by Allergy and Infectious Diseases 2010 - 2015
- Regulation of juvenile hormone titers in mosquitoes awarded by Allergy and Infectious Diseases 2010 - 2011
- Signaling Pathways That Regulate Juvenile Hormone Synthesis in Mosquitoes awarded by Allergy and Infectious Diseases 2009 - 2010
- Regulation of Juvenile Hormone Titers in Mosquitoes. awarded by Allergy and Infectious Diseases 2005 - 2010
co-principal investigator on
- Role of miRNAs on the regulation of juvenile hormone synthesis in mosquitoes awarded by Allergy and Infectious Diseases 2020 - 2022
- Regulation of juvenile hormone titers in mosquitoes awarded by Allergy and Infectious Diseases 2015 - 2022
- Southeastern Regional CoE in Vector-Borne Diseases: The Gateway Program awarded by Disease Control and Prevention 2016 - 2021
investigator on
Contact
full name
- Fernando Noriega
Identifiers
ORCID iD
- https://orcid.org/0000-0001-8628-5374 (confirmed)
visualizations
publication subject areas
- Biochemistry & Molecular Biology
- Biotechnology & Applied Microbiology
- Cell Biology
- Chemistry
- Endocrinology & Metabolism
- Entomology
- Environmental Sciences & Ecology
- Evolutionary Biology
- Life Sciences & Biomedicine - Other Topics
- Parasitology
- Pharmacology & Pharmacy
- Physiology
- Public, Environmental & Occupational Health
- Science & Technology - Other Topics
- Spectroscopy
- Tropical Medicine