Ramella Roman, Jessica
- Associate Professor, Biomedical Engineering , College of Engineering and Computing

Overview
overview
- Dr. Jessica C. Ramella-Roman received an Electrical Engineering degree (Laurea) from the University of Pavia, Italy in 1993 and worked for five years in the semiconductor industry. She returned to academia in 1999 to pursue a Ph.D. degree in bio-optics with Dr. Steve Jacques and she received a Master’s and Ph.D. degree in Electrical Engineering from Oregon Health Science University in Portland, Oregon in 2004. She was a Post Doctoral Fellow at the Applied Physics Laboratory of the Johns Hopkins University from 2004 to 2005. She was then an Associate Professor at The Catholic University of America from 2005 to 2010 and an Associate Professor from 2010 to 2013. She is a Senior Research Scientist at the National Rehabilitation Hospital in Washington DC, and an Adjunct Professor in the School of Medicine at Johns Hopkins University. Since 2013, she has served an Associate Professor at Florida International University, in the Biomedical Engineering Department and an Associate Professor on the Research Scientist Track in the Department of Cellular Biology and in the Department of Ophthalmology.
research interests
- Biophotonics
Scholarly & Creative Works
selected publications
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Article
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2022Polarization enhanced laparoscope for improved visualization of tissue structural changes associated with peritoneal cancer metastasisFull Text via DOI: 10.1364/BOE.443926 Web of Science: 000750864600005
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2021Introduction of a 3 x 4 Mueller matrix decomposition methodFull Text via DOI: 10.1088/1361-6463/ac1622 Web of Science: 000680672200001
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2021Mueller matrix imaging for collagen scoring in mice model of pregnancyFull Text via DOI: 10.1038/s41598-021-95020-8 Web of Science: 000685197100005
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2020Design and implementation of a portable colposcope Mueller matrix polarimeterFull Text via DOI: 10.1117/1.JBO.25.11.116006 Web of Science: 000595595000016
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2020A Method to Quantify Tensile Biaxial Properties of Mouse Aortic Valve LeafletsFull Text via DOI: 10.1115/1.4046921 Web of Science: 000613295700001
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2020Depth-resolved Mueller matrix polarimetry microscopy of the rat corneaFull Text via DOI: 10.1364/BOE.402201 Web of Science: 000577572500043
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2020Development of Multifunctional Biopolymeric Auto-Fluorescent Micro- and Nanogels as a Platform for Biomedical ApplicationsFull Text via DOI: 10.3389/fbioe.2020.00315 Web of Science: 000535564500001
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2020Self validating Mueller matrix Micro-Mesoscope (SAMMM) for the characterization of biological mediaFull Text via DOI: 10.1364/OL.387747 Web of Science: 000526401600009
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2019Dyspigmented hypertrophic scars: Beyond skin colorFull Text via DOI: 10.1111/pcmr.12780 Web of Science: 000481578200004
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2019Elastin-Dependent Aortic Heart Valve Leaflet Curvature Changes During Cyclic FlexureFull Text via DOI: 10.3390/bioengineering6020039 Web of Science: 000475298500012
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2018Use of Mueller matrix colposcopy in the characterization of cervical collagen anisotropyFull Text via DOI: 10.1117/1.JBO.23.12.121605 Web of Science: 000463883500006
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2018Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosaFull Text via DOI: 10.1111/aos.13581 Web of Science: 000430912700016
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2017Use of Mueller matrix polarimetry and optical coherence tomography in the characterization of cervical collagen anisotropyFull Text via DOI: 10.1117/1.JBO.22.8.086010 Web of Science: 000410739500016
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2017Elastin Is Differentially Regulated by Pressure Therapy in a Porcine Model of Hypertrophic ScarFull Text via DOI: 10.1097/BCR.0000000000000413 Web of Science: 000391867500065
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2016A Monte Carlo Analysis of Error Associated With Two-Wavelength Algorithms for Retinal OximetryFull Text via DOI: 10.1167/iovs.16-20138 Web of Science: 000392380000080
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2016A new approach for optical assessment of directional anisotropy in turbid mediaFull Text via DOI: 10.1002/jbio.201400124 Web of Science: 000367724100012
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2015Rapid prototyping of biomimetic vascular phantoms for hyperspectral reflectance imagingFull Text via DOI: 10.1117/1.JBO.20.12.121312 Web of Science: 000368440300015
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2015Biphasic Presence of Fibrocytes in a Porcine Hypertrophic Scar ModelFull Text via DOI: 10.1097/BCR.0000000000000097
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2015A Multimodal Assessment of Melanin and Melanocyte Activity in Abnormally Pigmented Hypertrophic ScarFull Text via DOI: 10.1097/BCR.0000000000000154 Web of Science: 000347456400013
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2015A portable automatic pressure delivery system for scar compression therapy in large animalsFull Text via DOI: 10.1063/1.4904842 Web of Science: 000349068700053
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2014A polarized multispectral imaging system for quantitative assessment of hypertrophic scarsFull Text via DOI: 10.1364/BOE.5.003337 Web of Science: 000343135200006
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2014In Vitro Evaluation of Fluorescence Glucose Biosensor ResponseFull Text via DOI: 10.3390/s140712127 Web of Science: 000340035700046
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2014Vascular contrast in narrow-band and white light imagingFull Text via DOI: 10.1364/AO.53.004061 Web of Science: 000338442800031
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2014Three-dimensional printing of tissue phantoms for biophotonic imagingFull Text via DOI: 10.1364/OL.39.003010 Web of Science: 000336982500048
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2013Monte Carlo modeling of light-tissue interactions in narrow band imagingFull Text via DOI: 10.1117/1.JBO.18.1.010504 Web of Science: 000315157000004
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2012Out-of-plane Stokes imaging polarimeter for early skin cancer diagnosisFull Text via DOI: 10.1117/1.JBO.17.7.076014
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2012Broadband ultraviolet-visible optical property measurement in layered turbid mediaFull Text via DOI: 10.1364/BOE.3.001226 Web of Science: 000304965700008
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2012Microfluidics based phantoms of superficial vascular networkFull Text via DOI: 10.1364/BOE.3.001350
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2011A new phenotypic manifestation of familial adenomatous polyposisFull Text via DOI: 10.1007/s10689-011-9432-3
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2011Spectroscopic sensitive polarimeter for biomedical applicationsFull Text via DOI: 10.1117/1.3561907
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2010Retinal spectral imaging and blood flow measurementFull Text via DOI: 10.1142/S1793545810001131
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2010Absolute blood velocity measured with a modified fundus cameraFull Text via DOI: 10.1117/1.3494565
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2010Use of a multi-spectral camera in the characterization of skin woundsFull Text via DOI: 10.1364/OE.18.003244
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2008Out of plane polarimetric imaging of skin: Surface and subsurface effectFull Text via DOI: 10.1007/978-1-4020-6952-9_12
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2007Spectroscopic measurements of oxygen saturation in the retinaFull Text via DOI: 10.1109/JSTQE.2007.911312
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2004Design, testing, and clinical studies of a handheld polarized light cameraFull Text via DOI: 10.1117/1.1781667
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2001Characterizing microscopic domains of birefringence in thin tissue sectionsFull Text via DOI: 10.1117/12.434735
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Book Chapter
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2012Monitoring of Blood Flow and Hemoglobin Oxygenation. 827-833.Full Text via DOI: 10.1002/9783527643981.bphot061
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2008Out of Plane Polarimetric Imaging of Skin: Surface and Subsurface Effect. 259-269.Full Text via DOI: 10.1007/978-1-4020-6952-9_12
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2008Polarized Light Transport into Scattering Media Using a Quaternion-Based Monte Carlo. 229-241.Full Text via DOI: 10.1007/978-1-4020-6952-9_10
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Conference
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2022Detection of cervical collagen remodeling with Mueller polarimetry in mice model of pregnancy. 16.Full Text via DOI: 10.1117/12.2610083
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2022A speculum free Portable Preterm Imaging System (PPRIM)Full Text via DOI: 10.1117/12.2609915 Web of Science: 000812215800009
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2022In-vivo human study of skin optical properties in individuals with obesityFull Text via DOI: 10.1117/12.2610464 Web of Science: 000832009400010
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2022Machine learning powered Mueller matrix microscope for collagen and elastin visualization in the mouse cervixFull Text via DOI: 10.1117/12.2609978 Web of Science: 000812215800010
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2021Polarized Light Imaging of the Pregnant Cervix.. 219A-219A.Web of Science: 000675441000446
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2021Synthetic photoplethysmographic waveform at the radial artery. 6.Full Text via DOI: 10.1117/12.2578951
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2020Polarized Light Imaging of the Pregnant Cervix.. 66A-67A.Web of Science: 000525432600023
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2020Design of wearable devices for diverse populations (Conference Presentation). 25.Full Text via DOI: 10.1117/12.2550356
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2020Parallelized multi-layered Monte Carlo Model for Evaluation of a Proximal Phalanx PhotoplethysmographFull Text via DOI: 10.1117/12.2543590 Web of Science: 000550790700001
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2019NIRS measurements of muscle oximetry in the obese (Conference Presentation). 21.Full Text via DOI: 10.1117/12.2508612
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2019Polarized light Monte Carlo simulation of cervical collagen ultrastructure (Conference Presentation). 23.Full Text via DOI: 10.1117/12.2508611
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2019Voxilization-based Monte Carlo simulation of the ischial tuberosity (Conference Presentation). 16.Full Text via DOI: 10.1117/12.2510250
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2018
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2018A low cost portable Mueller Matrix polarimeter for the low resource settingFull Text via DOI: 10.1117/12.2290592 Web of Science: 000453073000015
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2018Multiphoton microscopy of ECM proteins in baboon aortic leafletFull Text via DOI: 10.1117/12.2291024 Web of Science: 000435025800005
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2018Optimization of the incident wavelength for Mueller matrix imaging of cervical collagenFull Text via DOI: 10.1117/12.2290766 Web of Science: 000451703500003
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2018Calibration of low cost, portable Mueller Matrix polarimeterFull Text via DOI: 10.1364/TRANSLATIONAL.2018.JTu3A.6
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2017Handheld SFDI/polarimetric imaging device for objective evaluation of hypertrophic scars (Conference Presentation)Full Text via DOI: 10.1117/12.2251001 Web of Science: 000406427900003
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2017Quantitative Analysis of a Scar's Pliability, Perfusion and MetrologyFull Text via DOI: 10.1117/12.2252676 Web of Science: 000405955800008
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2017Use of Mueller matrix Polarimetry and Optical Coherence Tomography in the characterization of cervical collagen anisotropyFull Text via DOI: 10.1117/12.2250969 Web of Science: 000405823100021
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2017Use of Mueller matrix colposcopy in the characterization of cervical collagen anisotropyFull Text via DOI: 10.1117/12.2250987 Web of Science: 000405823100002
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2016
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2016Cervical Collagen Imaging for Determining Preterm Labor Risks Using a Colposcope with Full Mueller Matrix CapabilityFull Text via DOI: 10.1117/12.2213387 Web of Science: 000377396200112
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2016Imaging and modeling of collagen architecture in living tissue with polarized light transfer (Conference Presentation)Full Text via DOI: 10.1117/12.2213222 Web of Science: 000379313700003
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2016Imaging of skin surface architecture with out of plane polarimetryFull Text via DOI: 10.1117/12.2213365 Web of Science: 000377396200010
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2016Polarized light in birefringent samplesFull Text via DOI: 10.1117/12.2213335 Web of Science: 000377396200008
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2015
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20153D Printed Biomimetic Vascular Phantoms for Assessment of Hyperspectral Imaging SystemsFull Text via DOI: 10.1117/12.2084720 Web of Science: 000353883600005
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2015Preferential alignment of birefringent tissue measured with polarization sensitive techniquesFull Text via DOI: 10.1117/12.2081338 Web of Science: 000354366400006
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2015The role of camera and illumination choices in absolute blood velocity measurementsFull Text via DOI: 10.1117/12.2081340 Web of Science: 000353882000021
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2014Construction of a digital and physical mouse model aimed at the study of electrical shockFull Text via DOI: 10.1117/12.2039661 Web of Science: 000334097200006
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2014Quantitative Assessment of Biophotonic Imaging System Performance with Phantoms Fabricated by Rapid PrototypingFull Text via DOI: 10.1117/12.2044089 Web of Science: 000334099600012
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2014The efficacy of Pressure Relief Maneuvers in Spinal Cord Injury Patients, a clinical studyFull Text via DOI: 10.1117/12.2039545 Web of Science: 000334100600019
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2014Assessment of the Natural History of Treated and Untreated Scars with a Novel Imaging System. bm2b.1.Full Text via DOI: 10.1364/biomed.2014.bm2b.1
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2013A novel spectral imaging system for quantitative analysis of hypertrophic scarFull Text via DOI: 10.1117/12.2006096
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2013Quantitative transverse flow assessment using OCT speckle decorrelation analysisFull Text via DOI: 10.1117/12.2006920
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2013Characterization and Application of 3D Printed Phantoms for Biophotonic ImagingFull Text via DOI: 10.1117/12.2018285 Web of Science: 000329624600024
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2013Skin Microvascular and Metabolic Response to Pressure Relief Maneuvers in People with Spinal Cord InjuryFull Text via DOI: 10.1117/12.2006260 Web of Science: 000319682300018
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2013Monitoring the impact of pressure on the assessment of skin perfusion and oxygenation using a novel pressure deviceFull Text via DOI: 10.1117/12.2006256 Web of Science: 000322740800017
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2013Spectral Variations in Narrow Band Imaging Depth-Selectivity: Mucosal Scattering vs. Hemoglobin AbsorptionFull Text via DOI: 10.1117/12.2008768 Web of Science: 000340666700009
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2012Development and testing of a fluorescence biosensor for glucose sensingFull Text via DOI: 10.1117/12.920699
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2012Fabrication of microfluidic vascular phantoms by laser micromachiningFull Text via DOI: 10.1117/12.920805
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2012Quantitative Evaluation of Mucosal Vascular Contrast in Narrow Band Imaging Using Monte Carlo ModelingFull Text via DOI: 10.1117/12.918375 Web of Science: 000306053200005
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2012Visualization of Mucosal Vasculature with Narrow Band Imaging: A Theoretical StudyFull Text via DOI: 10.1117/12.906817 Web of Science: 000302534400002
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2011Hemispherical Stokes polarimeter for early cancer diagnosisFull Text via DOI: 10.1117/12.873608
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2011Broadband UV-Vis optical property measurement in layered turbid mediaFull Text via DOI: 10.1117/12.879647 Web of Science: 000291793300007
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2011A novel instrument aimed at measuring hypertrophic scar formationFull Text via DOI: 10.1088/1742-6596/277/1/012002
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2010A novel model of skin electrical injury. 504-507.Full Text via DOI: 10.1007/978-3-642-14998-6_129
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2010An imaging pulse oximeter based on a multi-aperture camera. 329-331.Full Text via DOI: 10.1007/978-3-642-14998-6_84
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2010Oximetry and blood flow in the retina. 321-324.Full Text via DOI: 10.1007/978-3-642-14998-6_82
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2009Imaging spectroscopy with a multi-aperture camera. 209-210.Full Text via DOI: 10.1109/LEOS.2009.5343318
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2009Spectroscopic Stokes vector polarimetry for biomedical applications. 463-464.Full Text via DOI: 10.1109/LEOS.2009.5343183
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2009Improvement of a snapshot spectroscopic retinal multi-aperture imaging cameraFull Text via DOI: 10.1117/12.811565
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2009Assessment of skin wound healing with a multi-aperture cameraFull Text via DOI: 10.1117/12.808956
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2008Optical properties of a new inorganic liquid crystal. 77-78.Full Text via DOI: 10.1109/LEOSST.2008.4590497
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2008Detection of blood oxygen level by noninvasive passive spectral imaging of skinFull Text via DOI: 10.1117/12.768708
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2008Polarized fluorescence for skin cancer diagnostic with a multi-aperture cameraFull Text via DOI: 10.1117/12.768536
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2007Truncated singular value decomposition method for calibrating a Stokes PolarimeterFull Text via DOI: 10.1117/12.734452
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2007A lenslet-based device for measuring oxygen saturation in the retinaFull Text via DOI: 10.1117/12.714123
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2005Out-of-plane polarimetric imaging of skin: Surface and subsurface effects. 142-153.Full Text via DOI: 10.1117/12.592399
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2003A hand-held polarized-light camera for the detection of skin cancer borders. 54-60.Full Text via DOI: 10.1117/12.534100
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2002Imaging skin with polarized light. 2314-2315.
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2002
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2001Mueller matrix description of collimated light transmission through liver, muscle and skin. 110-116.Full Text via DOI: 10.1117/12.434693
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Other Scholarly Work
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2021Special Section Guest Editorial: Wearable, Implantable, Mobile, and Remote Biomedical Optics and PhotonicsFull Text via DOI: 10.1117/1.JBO.26.6.062701 Web of Science: 000670421700004
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2018Pioneer in Biomedical Optics: Introduction to the Special Section in Honor of Steven L. JacquesFull Text via DOI: 10.1117/1.JBO.23.12.121601 Web of Science: 000463883500002
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2016Polarized Light for Biomedical ApplicationsFull Text via DOI: 10.1117/1.JBO.21.7.071001 Web of Science: 000381917800003
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Preprint
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Proceedings Paper
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2000Propagation of polarized light beams through biological tissues. 345-352.Full Text via DOI: 10.1117/12.388061
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Review
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2021Sources of Inaccuracy in Photoplethysmography for Continuous Cardiovascular MonitoringFull Text via DOI: 10.3390/bios11040126 Web of Science: 000642802400001
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2020A review of polarization-based imaging technologies for clinical and preclinical applicationsFull Text via DOI: 10.1088/2040-8986/abbf8a Web of Science: 000588564500001
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2019Optical phantoms for biomedical polarimetryFull Text via DOI: 10.1117/1.JBO.24.3.030901 Web of Science: 000463886200003
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2016A review of engineering approaches for lymphedema detection. 79-90.Full Text via DOI: 10.1109/RBME.2016.2582178
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2015Noninvasive imaging technologies for cutaneous wound assessment: A review. 149-162.Full Text via DOI: 10.1111/wrr.12262 Web of Science: 000356452000163
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2010Critical review of burn depth assessment techniques: Part ii. review of laser doppler technology. 151-157.Full Text via DOI: 10.1097/BCR.0b013e3181c7ed60
Research
principal investigator on
- Science and Technology Center on Real-Time Functional Imaging (STROBE) awarded by National Science Foundation 2021 - 2026
- NSF ERC: Precise Advanced Technologies and Health Systems for Underserved Populations (PATHS-UP) awarded by National Science Foundation 2017 - 2022
- Science and Technology Center on Real-Time Functional Imaging (STROBE) awarded by National Science Foundation 2016 - 2022
- An adaptive optics two photon microscope for retinal imaging awarded by DrHerbert & Nicole Wertheim Family Found 2016 - 2020
- NRT-IGE: Nanomedicine Academy awarded by National Science Foundation 2015 - 2018
- Rehabilitation Research and Training Center on Secondary Conditions in Rehabilitation of Individuals with Spinal Cord Injury - R3 awarded by U.S. Department of Education 2013 - 2015
- Creation of a Novel Imaging System to Objectively Assess the Natural History of Treated and Unt awarded by Biomedical Imaging and Bioengineering 2013 - 2014
co-principal investigator on
- Development of a Biosensing Platform for Vascular Calcification awarded by National Science Foundation 2017 - 2022
- FIU I-Corps Teams Funding awarded by National Science Foundation 2016
subproject principal investigator on
- Carbon nanotube based nanofluidic device for biological sensing awarded by National Science Foundation 2013 - 2018
Contact
full name
- Jessica Ramella Roman
visualizations
publication subject areas
Citation index-derived subject areas the researcher has published in