Ramella Roman, Jessica
- Associate Professor, Biomedical Engineering , College of Engineering and Computing

Overview
overview
- Dr. Jessica C. Ramella-Roman received an Electrical Engineering degree (Laurea) from the University of Pavia, Italy in 1993 and worked for five years in the semiconductor industry. She returned to academia in 1999 to pursue a Ph.D. degree in bio-optics with Dr. Steve Jacques and she received a Master’s and Ph.D. degree in Electrical Engineering from Oregon Health Science University in Portland, Oregon in 2004. She was a Post Doctoral Fellow at the Applied Physics Laboratory of the Johns Hopkins University from 2004 to 2005. She was then an Associate Professor at The Catholic University of America from 2005 to 2010 and an Associate Professor from 2010 to 2013. She is a Senior Research Scientist at the National Rehabilitation Hospital in Washington DC, and an Adjunct Professor in the School of Medicine at Johns Hopkins University. Since 2013, she has served an Associate Professor at Florida International University, in the Biomedical Engineering Department and an Associate Professor on the Research Scientist Track in the Department of Cellular Biology and in the Department of Ophthalmology.
research interests
- Biophotonics
Scholarly & Creative Works
selected publications
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Article
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2021Introduction of a 3 x 4 Mueller matrix decomposition methodFull Text via DOI: 10.1088/1361-6463/ac1622
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2021Synthetic photoplethysmography (PPG) of the radial artery through parallelized Monte Carlo and its correlation to body mass index (BMI). SCIENTIFIC REPORTS. 11.Full Text via DOI: 10.1038/s41598-021-82124-4 Web of Science: 000616821300080
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2020Design and implementation of a portable colposcope Mueller matrix polarimeter. JOURNAL OF BIOMEDICAL OPTICS. 25.Full Text via DOI: 10.1117/1.JBO.25.11.116006 Web of Science: 000595595000016
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2020A Method to Quantify Tensile Biaxial Properties of Mouse Aortic Valve Leaflets. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME. 142.Full Text via DOI: 10.1115/1.4046921 Web of Science: 000613295700001
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2020Depth-resolved Mueller matrix polarimetry microscopy of the rat cornea. BIOMEDICAL OPTICS EXPRESS. 11:5982-5994.Full Text via DOI: 10.1364/BOE.402201 Web of Science: 000577572500043
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2020Development of Multifunctional Biopolymeric Auto-Fluorescent Micro- and Nanogels as a Platform for Biomedical Applications. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 8.Full Text via DOI: 10.3389/fbioe.2020.00315 Web of Science: 000535564500001
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2020Self validating Mueller matrix Micro-Mesoscope (SAMMM) for the characterization of biological media. OPTICS LETTERS. 45:2168-2171.Full Text via DOI: 10.1364/OL.387747 Web of Science: 000526401600009
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2019Dyspigmented hypertrophic scars: Beyond skin color. PIGMENT CELL & MELANOMA RESEARCH. 32:643-656.Full Text via DOI: 10.1111/pcmr.12780 Web of Science: 000481578200004
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2018Key Cell Functions are Modulated by Compression in an Animal Model of Hypertrophic Scar. WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE. 30:353-+.Web of Science: 000484068600003
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2018Use of Mueller matrix colposcopy in the characterization of cervical collagen anisotropy. JOURNAL OF BIOMEDICAL OPTICS. 23.Full Text via DOI: 10.1117/1.JBO.23.12.121605 Web of Science: 000463883500006
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2018Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosa. ACTA OPHTHALMOLOGICA. 96:E366-E376.
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2017Elastin Is Differentially Regulated by Pressure Therapy in a Porcine Model of Hypertrophic Scar. JOURNAL OF BURN CARE & RESEARCH. 38:28-35.
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2017Quantitative assessment of hemodynamic and structural characteristics of in vivo brain tissue using total diffuse reflectance spectrum measured in a non-contact fashion. BIOMEDICAL OPTICS EXPRESS. 8:78-103.
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2017Use of Mueller matrix polarimetry and optical coherence tomography in the characterization of cervical collagen anisotropy. JOURNAL OF BIOMEDICAL OPTICS. 22.
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2016A Monte Carlo Analysis of Error Associated With Two-Wavelength Algorithms for Retinal Oximetry. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 57:6474-6481.
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2016A new approach for optical assessment of directional anisotropy in turbid media. JOURNAL OF BIOPHOTONICS. 9:100-108.
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2015A Multimodal Assessment of Melanin and Melanocyte Activity in Abnormally Pigmented Hypertrophic Scar. JOURNAL OF BURN CARE & RESEARCH. 36:77-86.
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2015A portable automatic pressure delivery system for scar compression therapy in large animals. REVIEW OF SCIENTIFIC INSTRUMENTS. 86.
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2015Assessment of oxygen saturation in retinal vessels of normal subjects and diabetic patients with and without retinopathy using Flow Oximetry System. QUANTITATIVE IMAGING IN MEDICINE AND SURGERY. 5:86-96.Full Text via DOI: 10.3978/j.issn.2223-4292.2014.11.26 PMID: 25694958 Web of Science: 000214946600012
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2015Rapid prototyping of biomimetic vascular phantoms for hyperspectral reflectance imaging. JOURNAL OF BIOMEDICAL OPTICS. 20.
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2014A polarized multispectral imaging system for quantitative assessment of hypertrophic scars. BIOMEDICAL OPTICS EXPRESS. 5:3337-3354.
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2014Three-dimensional printing of tissue phantoms for biophotonic imaging. OPTICS LETTERS. 39:3010-3013.
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Conference
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2002Imaging skin with polarized light. 2314-2315.
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2002
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Editorial Material
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2018Pioneer in Biomedical Optics: Introduction to the Special Section in Honor of Steven L. Jacques. JOURNAL OF BIOMEDICAL OPTICS.Full Text via DOI: 10.1117/1.JBO.23.12.121601 Web of Science: 000463883500002
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Meeting Abstract
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2020Polarized Light Imaging of the Pregnant Cervix.. REPRODUCTIVE SCIENCES. 66A-67A.Web of Science: 000525432600023
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2018Measurements of retinal temperature using Laser Speckle Imaging (LSI). INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.Web of Science: 000442932807319
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2018Simultaneous second harmonic generation and Mueller Matrix polarimetry imaging of the rat cornea. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.Web of Science: 000442932806405
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2016Increased Velocity of Retinal Blood Flow in RP subjects with Significantly Improved Visual Function following Transcorneal Electrical Stimulation in a Randomized Controlled Trial. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.Web of Science: 000394174000132
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2016Transcriptome profiles of porcine skin dyschromia after wound injury. FASEB JOURNAL.Web of Science: 000406444002163
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2015Error analysis of two-wavelength algorithms for retinal oximetry. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.Web of Science: 000362891100178
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Preprint
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Proceedings Paper
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2020Experimental integration of a Spatial Frequency Domain Spectroscopy and Pulse Cam system for quantifying changes in skin optical properties and vasculature among individuals with obesity. PHOTONICS IN DERMATOLOGY AND PLASTIC SURGERY 2020.Full Text via DOI: 10.1117/12.2546642 Web of Science: 000546474000002
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2020Modeling of a Photoplethysmographic (PPG) Waveform through Monte Carlo as a method of deriving Blood Pressure in Individuals with Obesity. OPTICAL INTERACTIONS WITH TISSUE AND CELLS XXXI.Full Text via DOI: 10.1117/12.2546589 Web of Science: 000554550700005
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2020Parallelized multi-layered Monte Carlo Model for Evaluation of a Proximal Phalanx Photoplethysmograph. OPTICAL DIAGNOSTICS AND SENSING XX: TOWARD POINT-OF-CARE DIAGNOSTICS.Full Text via DOI: 10.1117/12.2543590 Web of Science: 000550790700001
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2018A low cost portable Mueller Matrix polarimeter for the low resource setting. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2290592 Web of Science: 000453073000015
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2018Multiphoton microscopy of ECM proteins in baboon aortic leafletFull Text via DOI: 10.1117/12.2291024 Web of Science: 000435025800005
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2018Optimization of the incident wavelength for Mueller matrix imaging of cervical collagen. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2290766 Web of Science: 000451703500003
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2017Handheld SFDI/polarimetric imaging device for objective evaluation of hypertrophic scars (Conference Presentation). MOLECULAR-GUIDED SURGERY: MOLECULES, DEVICES, AND APPLICATIONS III.Full Text via DOI: 10.1117/12.2251001 Web of Science: 000406427900003
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2017Quantitative Analysis of a Scar's Pliability, Perfusion and Metrology. OPTICAL ELASTOGRAPHY AND TISSUE BIOMECHANICS IV.Full Text via DOI: 10.1117/12.2252676 Web of Science: 000405955800008
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2017Use of Mueller matrix Polarimetry and Optical Coherence Tomography in the characterization of cervical collagen anisotropy. DIAGNOSIS AND TREATMENT OF DISEASES IN THE BREAST AND REPRODUCTIVE SYSTEM.Full Text via DOI: 10.1117/12.2250969 Web of Science: 000405823100021
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2017Use of Mueller matrix colposcopy in the characterization of cervical collagen anisotropy. DIAGNOSIS AND TREATMENT OF DISEASES IN THE BREAST AND REPRODUCTIVE SYSTEM.Full Text via DOI: 10.1117/12.2250987 Web of Science: 000405823100002
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2016Cervical Collagen Imaging for Determining Preterm Labor Risks Using a Colposcope with Full Mueller Matrix Capability. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2213387 Web of Science: 000377396200112
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2016Imaging and modeling of collagen architecture in living tissue with polarized light transfer (Conference Presentation). ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2213222 Web of Science: 000379313700003
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2016Imaging of skin surface architecture with out of plane polarimetry. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2213365 Web of Science: 000377396200010
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2016Polarized light in birefringent samples. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2213335 Web of Science: 000377396200008
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20153D Printed Biomimetic Vascular Phantoms for Assessment of Hyperspectral Imaging Systems. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2084720 Web of Science: 000353883600005
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2015Preferential alignment of birefringent tissue measured with polarization sensitive techniques. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2081338 Web of Science: 000354366400006
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2015The role of camera and illumination choices in absolute blood velocity measurements. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2081340 Web of Science: 000353882000021
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2014Construction of a digital and physical mouse model aimed at the study of electrical shock. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2039661 Web of Science: 000334097200006
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2014Quantitative Assessment of Biophotonic Imaging System Performance with Phantoms Fabricated by Rapid Prototyping. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2044089 Web of Science: 000334099600012
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2014The efficacy of Pressure Relief Maneuvers in Spinal Cord Injury Patients, a clinical study. ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS VII.Full Text via DOI: 10.1117/12.2039545 Web of Science: 000334100600019
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Review
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2020A review of polarization-based imaging technologies for clinical and preclinical applications. JOURNAL OF OPTICS.Full Text via DOI: 10.1088/2040-8986/abbf8a Web of Science: 000588564500001
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2019Optical phantoms for biomedical polarimetry. JOURNAL OF BIOMEDICAL OPTICS.Full Text via DOI: 10.1117/1.JBO.24.3.030901 Web of Science: 000463886200003
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2015Noninvasive imaging technologies for cutaneous wound assessment: A review. WOUND REPAIR AND REGENERATION. 149-162.
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Research
principal investigator on
- Science and Technology Center on Real-Time Functional Imaging (STROBE) awarded by National Science Foundation 2021 - 2026
- NSF ERC: Precise Advanced Technologies and Health Systems for Underserved Populations (PATHS-UP) awarded by National Science Foundation 2017 - 2022
- Science and Technology Center on Real-Time Functional Imaging (STROBE) awarded by National Science Foundation 2016 - 2022
- An adaptive optics two photon microscope for retinal imaging awarded by DrHerbert & Nicole Wertheim Family Found 2016 - 2020
- NRT-IGE: Nanomedicine Academy awarded by National Science Foundation 2015 - 2018
- Rehabilitation Research and Training Center on Secondary Conditions in Rehabilitation of Individuals with Spinal Cord Injury - R3 awarded by U.S. Department of Education 2013 - 2015
- Creation of a Novel Imaging System to Objectively Assess the Natural History of Treated and Unt awarded by Biomedical Imaging and Bioengineering 2013 - 2014
co-principal investigator on
- Development of a Biosensing Platform for Vascular Calcification awarded by National Science Foundation 2017 - 2022
- FIU I-Corps Teams Funding awarded by National Science Foundation 2016
subproject principal investigator on
- Carbon nanotube based nanofluidic device for biological sensing awarded by National Science Foundation 2013 - 2018
Contact
full name
- Jessica Ramella Roman
visualizations
Recent publications and grants in Scholars@FIU
publication subject areas
Citation index-derived subject areas the researcher has published in