Rodriguez Martinez, Myosotys
- Assistant Professor, Immunology and Nano-Medicine , Herbert Wertheim College of Medicine

Overview
overview
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Myosotys Rodriguez is an Assistant Professor in the Department of Immunology and Nano-Medicine at Herbert Wertheim College of Medicine, Florida International University. She received her Ph.D. in Cellular and Molecular Biology from the Department of Microbiology and Immunology, Universidad Central del Caribe School of Medicine, Puerto Rico in 2014. Her doctoral research involved examining the effects of opioid dependence treatment in HIV immunopathology in the peripheral immune system and the central nervous system (CNS).
Dr. Rodriguez joined FIU in 2015 to pursue postdoctoral training under the mentorship of Dr. Nazira El-Hage. As a postdoctoral fellow her training was focused in demonstrating that autophagy is an essential mechanism through which HIV replication is mediated in the CNS. Specifically, how imbalances in autophagy alter HIV and opiates-induced astroglia metabolic dysfunctions.
research interests
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Investigating whether targeting autophagy lessen the metabolic dysfunctions induced by HIV within the brain in the presence of antiretroviral therapy
The use of nanotherapy to attenuate HIV and neuroinflammation
Scholarly & Creative Works
selected publications
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Article
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2021Targeting Beclin1 as an Adjunctive Therapy against HIV Using Mannosylated Polyethylenimine NanoparticlesFull Text via DOI: 10.3390/pharmaceutics13020223 Web of Science: 000623002300001
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2020Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology during PregnancyFull Text via DOI: 10.3390/v12060608 Web of Science: 000551247500001
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2020Comparative Cytotoxicity of Inorganic Arsenite and Methylarsenite in Human Brain CellsFull Text via DOI: 10.1021/acschemneuro.9b00653 Web of Science: 000518702400007
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2019Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytesFull Text via DOI: 10.1371/journal.pone.0208543 Web of Science: 000458181200007
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Conference
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2018
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2017
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2016ROLE OFAUTOPHAGYON HIV-INFECTED HUMAN ASTROCYTES FUNCTIONALITY.. S41-S41.Web of Science: 000377566000105
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Other Scholarly Work
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2022GDNF-expressing macrophages restore motor functions at a severe late-stage and produce long-term neuroprotective effects at an early-stage of Parkinson's disease in transgenic Parkin Q311X(A) mice (vol 315, pg 139, 2019). 813-814.Full Text via DOI: 10.1016/j.jconrel.2022.01.007 Web of Science: 000802746900001
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Review
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2018Autophagy, EVs, and Infections: A Perfect Question for a Perfect TimeFull Text via DOI: 10.3389/fcimb.2018.00362 Web of Science: 000447588800001
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2018Complementary Mechanisms Potentially Involved in the Pathology of Zika VirusFull Text via DOI: 10.3389/fimmu.2018.02340 Web of Science: 000447256100001
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2017HIV-1 Transcription Inhibitors Increase the Synthesis of Viral Non-Coding RNA that Contribute to Latency. 4133-4144.Full Text via DOI: 10.2174/1381612823666170622101319 Web of Science: 000414366900008
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2016Mammalian microRNA: an important modulator of host-pathogen interactions in human viral infectionsFull Text via DOI: 10.1186/s12929-016-0292-x Web of Science: 000386719500001
Contact
full name
- Myosotys Rodriguez Martinez
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publication subject areas
Citation index-derived subject areas the researcher has published in