Dr. Manivannan Yegambaram is Research Assistant Professor at Florida International University’s Center for Translational Science. Dr. Manivannan earned his Bachelor's degree in Zoology from Fergusson College and Master's degree in Health Sciences from University of Pune in India. He received Victoria University of Wellington Doctoral Scholarship and completed his PhD degree in Cell and Molecular Biology from Victoria University of Wellington in New Zealand. His PhD research under Prof. Paul Atkinson focused on localizing misfolded glycoproteins in the cells arising from a disorder of glycosylation using the Perkin Elmer Evotec Opera high content screening microscope. After obtaining PhD degree, he moved to USA and held two postdoctoral fellowships. First, he worked with Prof. Rolf Halden at the Arizona State University and established the Proteomics and Mass Spectrometry recharge facility. He focused on assessment of bioaccumulative and toxic organic environmental pollutants in tissue of Alzheimer's disease patients. Utilizing LC-MS, GC-MS and MALDI-TOF mass spectrometry he identified organ-specific human body burdens to select environmental pollutants/toxicants suspected to constitute Alzheimer's disease risk factors. Later, he joined the College of Medicine at University of Arizona as a postdoctoral research associate and worked with Prof. Stephen Black to focus on Pulmonary hypertension and acute lung injury. Using MALDI-TOF mass spectrometry he identified post-translational modification signature profiles reflective of Pulmonary hypertension and acute lung injury. In 2021, he joined the Center for Translational Science at Florida International University as research assistant professor. He currently focuses on two research areas.
1. Post-translational modification of key proteins associated with Pulmonary hypertension and acute lung injury
2. Metabolic reprogramming in Pulmonary hypertension
- Proteomics, Mass spectrometry, Metabolomics, Microscopy, High throughput drug screening, Cell and Molecular Biology
Scholarly & Creative Works
Other Scholarly Work
- Manivannan Yegambaram