The outcome of pregnancy in patients with treated and untreated prolactin-secreting pituitary tumors Article

Hammond, CB, Haney, AF, Land, MR et al. (1983). The outcome of pregnancy in patients with treated and untreated prolactin-secreting pituitary tumors . 147(2), 148-157. 10.1016/0002-9378(83)90108-4

cited authors

  • Hammond, CB; Haney, AF; Land, MR; van der Merwe, JV; Ory, SJ; Wiebe, RH

fiu authors

abstract

  • Few data document pregnancy risks in patients with prolactin-secreting pituitary tumors, particularly risks relating to the likelihood and severity of increased tumor size. This study presents three groups of women with such lesions. Group 1 consisted of 47 women with transsphenoidal resection who were euprolactinemic postoperatively. Of this group 20 of 22 previously infertile women conceived 25 pregnancies. Group 2 was composed of 17 women who were operated upon but in whom prolactin was still raised (>50 ng/ml) postoperatively and bromocriptine was subsequently used. Seven of these 17 patients were previously infertile, and six of the seven have conceived. In group 3 22 infertile women with small pituitary tumors were not operated upon but received bromocriptine. Eighteen of these patients have achieved 24 pregnancies. Methods of diagnosis, surveillance during pregnancy, and medical and surgical management are presented. Only two patients, both in group 3, developed signs of expanding tumor size in pregnancy. © 1983.

publication date

  • September 15, 1983

Digital Object Identifier (DOI)

start page

  • 148

end page

  • 157

volume

  • 147

issue

  • 2