Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries Article

Kathiresan, ASQ, Ibrahim, E, Aballa, TC et al. (2011). Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries . 96(3), 562-566. 10.1016/j.fertnstert.2011.06.078



cited authors

  • Kathiresan, ASQ; Ibrahim, E; Aballa, TC; Attia, GR; Ory, SJ; Hoffman, DI; Maxson, WS; Barrionuevo, MJ; Lynne, CM; Brackett, NL

fiu authors

abstract

  • Objective: To determine if outcomes after in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) using sperm from men with spinal cord injury (SCI group) differ from those of other etiologies of male factor infertility (non-SCI group). In men with SCI, to determine if IVF/ICSI outcomes differ with sperm obtained by penile vibratory stimulation (PVS group) versus electroejaculation (EEJ group). Design: Retrospective analysis. Setting: University medical center and major infertility center. Patient(s): Couples with male factor infertility due to SCI versus other etiologies. Intervention(s): PVS, EEJ, surgical sperm retrieval, and IVF/ICSI. Main Outcome Measure(s): Rates of fertilization, pregnancy, and live birth. Result(s): A total of 31 couples in the SCI group underwent 48 cycles of IVF/ICSI, and a total of 297 couples in the non-SCI group underwent 443 cycles of IVF/ICSI. The SCI group had lower fertilization rates but similar pregnancy and live birth rates compared with the non-SCI group. These rates, however, did not differ significantly when the PVS group was compared with the EEJ group. Conclusion(s): IVF/ICSI of sperm from men with SCI yield lower fertilization rates but similar pregnancy and live birth outcomes as IVF/ICSI of sperm from men with other etiologies of male factor infertility. Sperm collected by PVS versus EEJ in men with SCI appear to result in similar IVF/ICSI success rates. Copyright © 2011 American Society for Reproductive Medicine, Published by Elsevier Inc.

publication date

  • September 1, 2011

Digital Object Identifier (DOI)

start page

  • 562

end page

  • 566

volume

  • 96

issue

  • 3