BACKGROUND/AIM: Papular dermatitis is a persistent pruritic papular dermatitis, often refractory to treatment. The objective was to examine the effectiveness of cyclosporin for the treatment of this condition. METHODS: A retrospective review was conducted of the medical records of a cohort of 16 patients with papular dermatitis who were treated with cyclosporin within the last 2 years. RESULTS: Twelve of the 16 patients improved. Of those who improved, two discontinued treatment because of side effects such as hypertension, infection, and tremors. In those that responded favorably, the cyclosporin was tapered slowly. Some patients, however, required continuous therapy due to relapse upon discontinuation of the cyclosporin. CONCLUSION: Cyclosporin is an effective treatment for papular dermatitis. (J Dermatol Treat (2000) 11: 253-257).