Robust spectral-domain optical coherence tomography speckle model and its cross-correlation coefficient analysis Article

cited authors

  • Liu, X; Ramella-Roman, JC; Huang, Y; Guo, Y; Kang, JU


  • In this study, we propose a generic speckle simulation for optical coherence tomography (OCT) signal, by convolving the point-spread function (PSF) of the OCT system with the numerically synthesized random sample field. We validate our model and use the simulation method to study the statistical properties of cross-correlation coefficients between A-scans, which have been recently applied in transverse motion analysis by our group. The results of simulation show that oversampling is essential for accurate motion tracking; exponential decay of OCT signal leads to an underestimate of motion that can be corrected; lateral heterogeneity of sample leads to an overestimate of motion for a few pixels corresponding to the structural boundary. © 2012 Optical Society of America.

publication date

  • January 1, 2013

Digital Object Identifier (DOI)

start page

  • 51

end page

  • 59


  • 30


  • 1