Preparation and evaluation of a new synthetic polymeric chiral stationary phase for HPLC based on the trans-9,10-dihydro-9,10-ethanoanthracene-(11S,12S)- 11,12-dicarboxylic acid bis-4-vinylphenylamide monomer Article

cited authors

  • Han, X; Wang, C; He, L; Beesley, TE; Armstrong, DW

fiu authors


  • A new synthetic polymeric chiral stationary phase for liquid chromatography was prepared via free-radical-initiated polymerization of trans-9,10-dihydro-9, 10-ethanoanthracene-(11S,12S)-11,12-dicarboxylic acid bis-4-vinylphenylamide. The new polymeric chiral stationary phase (CSP) showed enantioselectivity for many chiral compounds in multiple mobile phases. High stability and sample capacities were observed on this polymeric chiral stationary phase. Mobile phase components and additives affected chiral separation greatly. This new synthetic chiral stationary phase is complementary to two other related commercially available CSPs: the P-CAP and P-CAP-DP columns. Interactions between the chiral stationary phase and analytes that lead to retention and chiral recognition include hydrogen bonding, dipolar, and π-π interactions. Repulsive (steric) interactions also contribute to chiral recognition. [Figure not available: see fulltext.]. © Springer-Verlag 2007.

publication date

  • April 1, 2007

Digital Object Identifier (DOI)

start page

  • 2681

end page

  • 2697


  • 387


  • 8