Prediction of antigenic epitopes for coat protein of potato virus Y Conference

cited authors

  • Guo, SH; Wang, CL; Yang, HY; Zhang, NN; Zhuang, X; Cui, DZ

fiu authors

abstract

  • Potato virus Y (PVY) is one of the most important viruses that infect Solanaceous crops. In the study, the antigenic epitopes were predicted using computer-assisted analysis, and many potential regions of antigenic epitopes were located. Many properties of coat protein, such as the antigenic index, α-helix, β-sheet, β-turn, coil structure, hydrophilicity, surface probability, and flexibility, were analyzed with several algorithms in some softwares. Based on the rules for location the antigenic epitopes in the regions including β-turns and coil structures with the high hydrophilicity and surface probability, the predicted epitopes were located in the region of amino acid position 8-22, 24-38, 45-55, 240-255, respectively. It is helpful to prepare the antiserum of PVY based on the prediction result of antigenic epitope. © (2011) Trans Tech Publications.

publication date

  • February 14, 2011

start page

  • 1204

end page

  • 1208

volume

  • 183-185