Hypermodal cells, hypomodal cells, and repetitive abortions Article

Meyers, CM, Simpson, JL, Martin, AO et al. (1986). Hypermodal cells, hypomodal cells, and repetitive abortions . 46(4), 615-618. 10.1016/s0015-0282(16)49637-8



cited authors

  • Meyers, CM; Simpson, JL; Martin, AO; Elias, S

fiu authors

abstract

  • The frequency of neither hypermodal cells (2N = 47) nor hypomodal cells (2N = 45) differed between lymphocytes of individuals experiencing repetitive spontaneous abortions (N = 429) and controls (N = 90). The same conclusion held when data were analyzed according to chromosome involved (sex chromosome, autosome) or other variables (e.g., prior reproductive outcome). A study of this relatively large sample failed to confirm findings of smaller and sometimes uncontrolled studies. Hypermodal cells do not necessarily serve as a clue to meiotic instability and in turn probably do not identify couples at risk for recurrent aneuploidy.

publication date

  • January 1, 1986

Digital Object Identifier (DOI)

start page

  • 615

end page

  • 618

volume

  • 46

issue

  • 4