Genetics of diabetes mellitus (DM) and anomalies in offspring of diabetic mothers Article

cited authors

  • Simpson, JL

fiu authors

abstract

  • The relationship between maternal diabetes mellitus and fetal anomalies remains to be elucidated. Most studies have shown increased frequencies of anomalies in offspring of diabetic mothers. However, studies have usually not been prospective nor utilized appropriate controls. Moreover, no specific spectrum of anomalies has been consistently observed. Several pathogenic mechanisms responsible for anomalies can be postulated, but no direct evidence in man is available.

publication date

  • December 1, 1978

start page

  • 383

end page

  • 394

volume

  • 2

issue

  • 4