Parental chromosomal rearrangements associated with repetitive spontaneous abortions Article

cited authors

  • Simpson, JL; Elias, S; Martin, AO

fiu authors

abstract

  • Parental chromosomal rearrangements represent a well-established cause of repetitive spontaneous abortions. However, the frequency of parental translocations varies widely in reported series, suggesting differences in ascertainment. For this reason a sample of individuals (120 women, 104 men) who had experienced spontaneous abortions but neither stillborn nor anomalous liveborn infants was investigated. Only one translocation was detected (0.4% of individuals). The relatively low frequency of translocations in this series is probably a reflection of not only lack of coexisting stillborn or anomalous infants but also the referral pattern in this unit that facilitates routine analysis of all couples experiencing repetitive abortions. In addition, one woman showed a pericentric inversion.

publication date

  • January 1, 1981

Digital Object Identifier (DOI)

start page

  • 584

end page

  • 590

volume

  • 36

issue

  • 5