Prenatal diagnosis of cytogenetic disorders Article

Simpson, JL, Martin, AO. (1976). Prenatal diagnosis of cytogenetic disorders . 19(4), 841-853. 10.1097/00003081-197612000-00013

cited authors

  • Simpson, JL; Martin, AO

fiu authors


  • The chromosomal complements of a fetus can be determined by analysis of cultured amniotic fluid cells obtained by amniocentesis. Prenatal cytogenetic studies are presently indicated in three situations: history of a previous child with aneuploidy, increased maternal age, and a parent with a balanced translocation or an inversion. A major goal of reproductive geneticists is to identify individuals who have an increased risk of having offspring with chromosomal aberrations and, hence, to whom prenatal cytogenetic diagnosis should be offered.

publication date

  • January 1, 1976

Digital Object Identifier (DOI)

start page

  • 841

end page

  • 853


  • 19


  • 4