Genetic basis of endometriosis Conference

Bischoff, F, Simpson, JL. (2004). Genetic basis of endometriosis . 1034 284-299. 10.1196/annals.1335.030

cited authors

  • Bischoff, F; Simpson, JL

fiu authors


  • Endometriosis is a complex gynecologic disorder that has long been recognized as showing heritable tendencies, with recurrence risks of 5-7% for first-degree relatives. Familial and epidemiologic studies support that this disease is a genetic disorder of polygenic/multifactorial inheritance. The current investigational challenge is to determine the number and location of causative genes. Recent advances in molecular technology make identification and elucidation of these genes now possible. In this review, we update previous communications in which we also reviewed heritability studies supporting polygenic/multifactorial inheritance, discuss the scientific basis of genomewide strategies for identifying causative genes, and identify potential candidate genes. © 2004 New York Academy of Sciences.

publication date

  • January 1, 2004

Digital Object Identifier (DOI)

start page

  • 284

end page

  • 299


  • 1034