The main objective of this research was to examine HIV/AIDS related policies in Honduras, Ecuador, Dominican Republic, and Puerto Rico. We aimed to examine the legislative process and outcome in each country regarding health policies related to the epidemic. This study was motivated by the disastrous effects of the epidemic in the Americas and by the need to foster psychology's involvement in the development of these policies in our countries. We examined HIV/AIDS related legislation through the looking glass of the traditional tensions between the individual rights of those living with HIV/AIDS and the rest of society. It is our understanding that these policies not only represent concrete efforts to stop the epidemic, but also existing perspectives regarding social values and the description of the disease in our hemisphere. A comparison between these countries allowed us to examine the actions or lack of them, taken by different States in the Americas, the limitations of these efforts, and their successes. We propose some recommendations to collaborate with development of these policies in our countries and emphasize the importance of examining psychologists' participation in the political process.