Type of alcoholic beverage and risk of head and neck cancer--a pooled analysis within the INHANCE Consortium. Other Scholarly Work

Purdue, Mark P, Hashibe, Mia, Berthiller, Julien et al. (2009). Type of alcoholic beverage and risk of head and neck cancer--a pooled analysis within the INHANCE Consortium. . 169(2), 132-142. 10.1093/aje/kwn306

cited authors

  • Purdue, Mark P; Hashibe, Mia; Berthiller, Julien; La Vecchia, Carlo; Dal Maso, Luigino; Herrero, Rolando; Franceschi, Silvia; Castellsague, Xavier; Wei, Qingyi; Sturgis, Erich M; Morgenstern, Hal; Zhang, Zuo-Feng; Levi, Fabio; Talamini, Renato; Smith, Elaine; Muscat, Joshua; Lazarus, Philip; Schwartz, Stephen M; Chen, Chu; Neto, Jose Eluf; W√ľnsch-Filho, Victor; Zaridze, David; Koifman, Sergio; Curado, Maria Paula; Benhamou, Simone; Matos, Elena; Szeszenia-Dabrowska, Neonilia; Olshan, Andrew F; Lence, Juan; Menezes, Ana; Daudt, Alexander W; Mates, Ioan Nicolae; Pilarska, Agnieszka; Fabianova, Eleonora; Rudnai, Peter; Winn, Debbie; Ferro, Gilles; Brennan, Paul; Boffetta, Paolo; Hayes, Richard B

fiu authors

abstract

  • The authors pooled data from 15 case-control studies of head and neck cancer (9,107 cases, 14,219 controls) to investigate the independent associations with consumption of beer, wine, and liquor. In particular, they calculated associations with different measures of beverage consumption separately for subjects who drank beer only (858 cases, 986 controls), for liquor-only drinkers (499 cases, 527 controls), and for wine-only drinkers (1,021 cases, 2,460 controls), with alcohol never drinkers (1,124 cases, 3,487 controls) used as a common reference group. The authors observed similar associations with ethanol-standardized consumption frequency for beer-only drinkers (odds ratios (ORs) = 1.6, 1.9, 2.2, and 5.4 for < or =5, 6-15, 16-30, and >30 drinks per week, respectively; P(trend) < 0.0001) and liquor-only drinkers (ORs = 1.6, 1.5, 2.3, and 3.6; P < 0.0001). Among wine-only drinkers, the odds ratios for moderate levels of consumption frequency approached the null, whereas those for higher consumption levels were comparable to those of drinkers of other beverage types (ORs = 1.1, 1.2, 1.9, and 6.3; P < 0.0001). Study findings suggest that the relative risks of head and neck cancer for beer and liquor are comparable. The authors observed weaker associations with moderate wine consumption, although they cannot rule out confounding from diet and other lifestyle factors as an explanation for this finding. Given the presence of heterogeneity in study-specific results, their findings should be interpreted with caution.

publication date

  • January 1, 2009

keywords

  • Alcohol Drinking
  • Alcoholic Beverages
  • Beer
  • Case-Control Studies
  • Ethanol
  • Head and Neck Neoplasms
  • Humans
  • Odds Ratio
  • Risk Assessment
  • Risk Factors
  • Wine

Digital Object Identifier (DOI)

Medium

  • Print-Electronic

start page

  • 132

end page

  • 142

volume

  • 169

issue

  • 2