Potential magnetic nanotherapeutics for management of neuroAIDS Book Chapter

Sagar, V, Vashist, A, Nair, M. (2019). Potential magnetic nanotherapeutics for management of neuroAIDS . 4 34-60. 10.2174/9781681085265117040004

cited authors

  • Sagar, V; Vashist, A; Nair, M

fiu authors

abstract

  • The human immunodeficiency virus (HIV) infection into the brain induces neurotoxicity and neuropathology which are collectively termed as the neuroAIDS. Brain delivery of therapeutic molecules continues to be the greatest challenge, primarily because of the tightly-junctioned blood-brain barrier (BBB). Several nano-vehicles are under intensive examination for delivering drugs across the BBB. Magnetic nanoparticles (MNPs) possess advantages over their counterparts because of their potential utilization for non-invasive brain targeting using external magnetic force. MNPs can be physicochemically modulated for engineering smart drug delivery carrier as well. Nonetheless, rigorous research is required to fix associated shortcomings of MNPs before their real-time application.

publication date

  • January 1, 2019

Digital Object Identifier (DOI)

start page

  • 34

end page

  • 60

volume

  • 4